Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Differential equations and differential calculus in Montel spaces [PDF]
, 1964 E. Dubinsky
openalex +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
V. I. Smirmov, A Course of Higher Mathematics, Vol. I: Elementary Calculus, 546 pp., 90s.; Vol. II: Advanced Calculus, 632 pp., 90s.; Vol. III, Part 1: Linear Algebra, 326 pp., 63s.; Vol. III, Part 2: Complex Variables and Special Functions, 702 pp., 110s.; Vol. IV: Integral Equations and Partial Differential Equations, 814 pp., 126s. [PDF]
, 1969 D. Martin
openalex +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
The homotopy analysis method for q-difference equations
Ain Shams Engineering Journal, 2018 The q-difference equations are kind of important problems in q-calculus and applied mathematics. In this paper, the homotopy analysis method is extended to find approximate solution for some of q-differential equations.
Mourad S. Semary, Hany N. Hassan
doaj
Differential and integral calculus, by F. Erwe. Translation by B. Fishel of the 1964 German edition. Hafner Publishing Co., New York, 1967, x + 494 pages. U.S. $9. 25. [PDF]
, 1969 Hugh Thurston
openalex +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Calculus of variations and partial differential equations of the first order. Part II : Calculus of variations, by C. Carathéodory. (Translated from he German by Robert B. Dean). Holden-Day Inc., San Francisco, 1967, xvi + 398 pages. U.S. $10.75. [PDF]
, 1969 Hanno Rund
openalex +1 more source