Results 81 to 90 of about 196,816 (332)
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Differential Operators and Differential Calculus on $delta-$Hom-Jordan-Lie Superalgebras
پژوهشهای ریاضی, 2020 Introduction Hom-algebraic structures appeared first as a generalization of Lie algebras in [1,3], where the authors studied q-deformations of Witt and Virasoro algebras. A general study and construction of Hom-Lie algebras
Valiollah Khalili
doaj
Differential calculus on the h-superplane
Journal of Mathematical Physics, 1998 A noncommutative differential calculus on the h-superplane is presented via a contraction of the q-superplane. An R-matrix which satisfies both ungraded and graded Yang–Baxter equations is obtained and a new deformation of the (1+1)-dimensional classical phase space (the super-Heisenberg algebra) is introduced.
ÇELİK, Salih +2 more
openaire +5 more sources
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
A convenient setting for differential calculus
Journal of Pure and Applied Algebra, 1979 Cartesian closed categories play an important r6le in many aspects of mathematics. They appear in algebraic geometry, in logic, in topology. Quite naturally one is tempted to use this notion also for differential calculus. First attempts in this direction were undertaken by A. Bastiani [l] and then by A. Frolicher and W. Bucher [4].
Ulrich Seip, Ulrich Seip
openaire +3 more sources
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source