Results 71 to 80 of about 425,883 (279)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Simulating STM transport in alkanes from first principles
, 2009 Simulations of scanning tunneling microscopy measurements for molecules on surfaces are traditionally based on a perturbative approach, most typically employing the Tersoff-Hamann method.
C. Toher +3 more
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
A new Network Simulation Method for the characterization of delay differential equations
Ain Shams Engineering Journal, 2023 In this work, we provide for the first time the characterization of delay terms in systems of delay differential equations within the frame of the Network Simulation Method, a procedure that sets a formal equivalence between the system of differential ...
Manuel Caravaca Garratón +2 more
doaj +1 more source
Stable amplifier having a stable quiescent point Patent [PDF]
, 1969 Development of stable electronic amplifier adaptable for monolithic and thin film ...
Kleinberg, L. L.
core +1 more source
A high-resolution burst-mode laser transmitter with fast and accurate level monitoring for 1.25 Gb/s upstream GPONs [PDF]
, 2005 A
Bauwelinck, Johan +6 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Estimation of Signal Distortion Bias Using Geometry-Free Linear Combinations
Remote SensingSignal distortion bias (SDB) in Global Navigation Satellite System (GNSS) data processing, defined as the time difference between the distorted chip and the ideal rectangular chip, leads to systematic biases in pseudoranges, affecting satellite and ...
Mohammed Abou Galala, Wu Chen
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source