Results 61 to 70 of about 597,383 (289)

Numerical Verification of Affine Systems with up to a Billion Dimensions

open access: yes, 2019
Affine systems reachability is the basis of many verification methods. With further computation, methods exist to reason about richer models with inputs, nonlinear differential equations, and hybrid dynamics.
Alur Rajeev   +7 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Novel extended multivariate public key cryptosystem

open access: yesTongxin xuebao, 2014
To resist linearization attack and differential attack effectively, a nonlinear invertible transformation based on“tame transformation” was constructed.
Shuai-ting QIAO, Yi-fa LI, Wen-bao HAN
doaj   +2 more sources

Computation of iterative solutions along with stability analysis to a coupled system of fractional order differential equations

open access: yesAdvances in Difference Equations, 2019
In this research article, we investigate sufficient results for the existence, uniqueness and stability analysis of iterative solutions to a coupled system of the nonlinear fractional differential equations (FDEs) with highier order boundary conditions ...
Sajjad Ali   +4 more
doaj   +1 more source

Hyper-differential sensitivity analysis with respect to model discrepancy: Mathematics and computation

open access: yesCoRR, 2022
Model discrepancy, defined as the difference between model predictions and reality, is ubiquitous in computational models for physical systems. It is common to derive partial differential equations (PDEs) from first principles physics, but make simplifying assumptions to produce tractable expressions for the governing equations or closure models. These
Joseph L. Hart   +1 more
openaire   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Calibrating Data to Sensitivity in Private Data Analysis

open access: yes, 2014
We present an approach to differentially private computation in which one does not scale up the magnitude of noise for challenging queries, but rather scales down the contributions of challenging records.
Goldberg, Sharon   +2 more
core   +1 more source

Computational Analysis of Whole-Genome Differential Allelic Expression Data in Human

open access: yesPLoS Computational Biology, 2010
Allelic imbalance (AI) is a phenomenon where the two alleles of a given gene are expressed at different levels in a given cell, either because of epigenetic inactivation of one of the two alleles, or because of genetic variation in regulatory regions. Recently, Bing et al.
James R Wagner   +5 more
openaire   +4 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

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