Results 151 to 160 of about 6,922,407 (400)
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
DIFFERENTIAL DIAGNOSIS OF RHEUMATOID JOINT AFFECTIONS. [PDF]
JAMES B. HERRICK
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Nicorandil-induced oral ulceration [PDF]
Oral ulceration has many aetiological factors. The antianginal drug Nicorandil is becoming increasingly recognised as a causative factor for oral ulceration.
Ciantar, Marilou, Gibson, John
core
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Dermoscopy of Primary Localized Cutaneous Nodular Amyloidosis
Laura Manuela Pulgarin,1 Alessandro De Pellegrin,2 Giuseppe Stinco,3 Enzo Errichetti3 1Department of Dermatology, Universidad del Valle, Cali, Colombia; 2Department of Pathology, Udine “S.
Pulgarin LM+3 more
doaj
THE DIFFERENTIAL DIAGNOSIS OF SYPHILIS AND PARASYPHILIS OF THE NERVOUS SYSTEM: Introduction to a Discussion on Syphilis and Parasyphilis of the Nervous System at the Medical Society of London on November 13th, 1911 [PDF]
F. W. Mott
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Differential Diagnosis. Presented through an analysis of 317 cases [PDF]
Richard C. Cabot
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source