Determination of Arbitrary Moments of Aerosol Size Distributions from Measurements with a Differential Mobility Analyzer [PDF]
Kensei Ehara+2 more
openalex +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Differential Distribution and Determinants of Ammonia Oxidizing Archaea Sublineages in the Oxygen Minimum Zone off Costa Rica. [PDF]
Lu Y, Xia X, Cheung S, Jing H, Liu H.
europepmc +1 more source
Differential Distribution of cAMP Receptors cAR2 and cAR3 duringDictyosteliumDevelopment
Yimin Yu, Charles L. Saxe
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Differential distribution of G-protein-coupled receptor kinase types 2, 3, 4, 5, and 6 in human brain: an immunohistochemical analysis [PDF]
Hironobu Watanabe
openalex +1 more source
Differential distribution of IgA-protease genotypes in mucosal and invasive isolates of Haemophilus influenzae in Sweden. [PDF]
Resman F+4 more
europepmc +1 more source