Results 191 to 200 of about 4,228,827 (257)

A Highly Linear Analog-to-Spike Converter

Akbari M, Covi E.
europepmc   +1 more source

Leishmania major virulence attenuation in vitro: An old conundrum revisited in the omics era. [PDF]

PLoS Negl Trop Dis
Gerasimov ES, Záhonová K, Ishemgulova A, Novozhilova TS, Mishra SK, Kraeva N, Sádlová J, Volf P, Zimmer SL, Yurchenko V.   +9 more
europepmc   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Transcriptomic changes in the lacrimal glands of a Sjogren's disease animal model highlight key molecular mediators and altered biological functions underpinning glandular inflammation and hypofunction. [PDF]

Front Ophthalmol (Lausanne)
Toribio D, Morokuma J, Tai A, Zoukhri D.
europepmc   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Small Signaling Peptides in <i>Sorghum bicolor</i>: Integrating Phylogeny and Gene Expression to Characterize Roles in Stem Development. [PDF]

Plant Direct
Kurtz E, McKinley B, Mullet J.
europepmc   +1 more source

Integrated transcriptomic and metabolomic analysis reveals the central role of phenylpropanoid biosynthesis in pea resistance to powdery mildew. [PDF]

Front Plant Sci
Li Y, Lu J, Shao Y, Wang C, Zhang L, Min G.   +5 more
europepmc   +1 more source

Jasmonate signaling and prey nutrient availability trigger distinct biochemical responses in the Drosera capensis feeding cycle. [PDF]

Plant Physiol
Long ZG, Takahashi GR, Cumpio FM, Akbari OJ, Castelan U, Hadadian M, Le JV, Alemayhu AM, Einstein DE, Einstein EE, Kelz JI, Kwok AO, Pineda A, Shabakesaz P, Unhelkar MH, Woodcock SM, Butts CT, Martin RW.   +17 more
europepmc   +1 more source

Comparative transcriptomics and targeted metabolomics reveal mechanisms of leaf greenness retention during tobacco (Nicotiana tabacum L.) air-curing. [PDF]

BMC Plant Biol
Chang P, Liu Y, Chen X, Luo F, Hu H, Guo M, Du J, Meng L.   +7 more
europepmc   +1 more source

Senescent <i>Eimeria acervulina</i> Oocysts Maintain Transcriptional Activity During Extended Refrigerated Storage and Differentially Express Characteristic Genes. [PDF]

Microorganisms
Tucker MS, Naguib D, O'Brien CN, Yeager C, Rosenthal BM, Jenkins MC, Khan A.   +6 more
europepmc   +1 more source