Results 91 to 100 of about 382,650 (266)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Existence of Solution to Nonlinear Third-Order Differential Equation and Iterative Method Utilization via Graph-Based Contraction

Mathematics
A new kind of graph-based contraction in a metric space is introduced in this article. We investigate results concerning the best proximity points and fixed points for these contractions, supported by illustrated examples.
Kanyuta Poochinapan, Sompop Moonchai, Tanadon Chaobankoh, Phakdi Charoensawan   +3 more
doaj   +1 more source

Noise Removal Based on Fourth Order Partial Differential Equation

, 2008
Noise removal is an important image processing problem which has wide applications in different fields. The noise removal and edge preservation algorithm based on variational method and partial differential equation (PDE) for processing Magnetic ...
Zhifeng Wang, Du YK(杜英魁), Wang ZF(王智锋), Tang YD(唐延东), Yandong Tang, Yingkui Du   +5 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

On Some Novel Results About the Behavior of Some Numerical Solutions of a Neutrosophic Generalized Half – Linear Second Order Differential Equation [PDF]

Neutrosophic Sets and Systems
The generalized neutrosophic differential equation is a differential equation with neutrosophic real variable x + yI instead of classical real variable x. This research is devoted to studying the oscillation of generalized neutrosophic half linear second
Norah Mousa Alrayes, Norah Mousa Alrayes, Mutaz Mohamed Abbas Ali, Amani Shatarah, Mai Mousa Mahmoud Alhejoj, Abdallah Al-Husban   +5 more
doaj   +1 more source

Resolve the multitude of microscale interactions to holistically discretise the stochastically forced Burgers' partial differential equation [PDF]

, 2006
[Abstract]: Constructing discrete models of stochastic partial differential equations is very delicate. Here we use modern dynamical systems theory to derive spatial discretisations of the nonlinear advection-diffusion dynamics of the stochastically ...
Roberts, A. J.
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Design of partial differential equation hull surfaces using genetic algorithms

, 2005
The automatic generation of a range of flat-sided hull forms which satisfy constraints on various primary and secondary geometric parameters is considered. The curved section of each hull surface is generated using the Partial Differential Equation (PDE)
Lowe, Tim W.
core