Results 141 to 150 of about 6,715,931 (355)
Differential/Algebraic Equations As Stiff Ordinary Differential Equations
To a system of differential algebraic equations: \[ \text{(DAE)}\quad y'(t)=f(t,y(t),z(t),0),\quad g(t,y(t),z(t),0)=0, \] a system of singularly perturbed ordinary differential equations: \[ \text{(ODE)}\quad y_ \varepsilon'(t)=f(t,y_ \varepsilon(t),z_ \varepsilon(t),\varepsilon), \varepsilon z_ \varepsilon'(t)=g(t,y_ \varepsilon(t),z_ \varepsilon(t ...
openaire +3 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
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Recent trends in highly accurate and structure-preserving numerical methods for partial differential equations [PDF]
Quan Z. Sheng +3 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
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A Note on Homogenization of Ordinary Differential Equations with Delay Term [PDF]
Marcus Waurick, Michael Kaliske
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Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
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Asymptotic Limits of the Solutions of Linear Systems of Functional-Differential Equations with Linear and Constant Delays [PDF]
H. P. Pelyukh, D. V. Bel’skyi
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We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
A boundary value problem for a system of ordinary linear differential equations of the first order [PDF]
Gilbert Ames Bliss
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