Results 201 to 210 of about 1,822,413 (315)

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Age-structured malaria model with temperature-dependent dynamics and optimal control analysis within a partial differential equation framework. [PDF]

PLoS One
Petros LD, Abdisa TE, Etefa DT, Menbiko DK, Gizaw AK, Simma EA, Yewhalaw D, Deressa CT.   +7 more
europepmc   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

Bayesian spatiotemporal stochastic partial differential equation for high-resolution earthquake magnitude mapping: Application to Sumatra Island, Indonesia. [PDF]

MethodsX
Azuri DF, Jaya IGNM, Rosandi Y.
europepmc   +1 more source

Estimating and Assessing Differential Equation Models with Time-Course Data. [PDF]

J Phys Chem B, 2023
Wong SWK, Yang S, Kou SC.
europepmc   +1 more source

A first order method for differential equations of neutral type [PDF]

, 1973
R. N. Castleton, L. J. Grimm
openalex   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Physiology-informed regularisation enables training of universal differential equation systems for biological applications. [PDF]

PLoS Comput Biol
de Rooij M, Erdős B, van Riel NAW, O'Donovan SD.   +3 more
europepmc   +1 more source

A new X-ray images enhancement method using a class of fractional differential equation. [PDF]

MethodsX, 2023
Aldoury RS, Al-Saidi NMG, Ibrahim RW, Kahtan H.   +3 more
europepmc   +1 more source

Asymptotic relationships between the solutions of two systems of differential equations [PDF]

, 1974
Miloš Ráb
openalex   +1 more source