Results 91 to 100 of about 227,477 (267)

Existence of maximal and minimal solutions initial value problem for the system of fractal differential equations

open access: yesBoundary Value Problems
Differential equation refers to an equation that includes a function and its derivatives. These equations serve to model real-world situations where rates of change are significant.
Mohammad Sajid   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A fractional differential equation model for continuous glucose monitoring data

open access: yesAdvances in Difference Equations, 2017
The main aim of this research was to test if fractional-order differential equation models could give better fits than integer-order models to continuous glucose monitoring (CGM) data from subjects with type 1 diabetes.
Sasikarn Sakulrang   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Ebola Outbreak Control Model Based on the Differential Equation

open access: yesChemical Engineering Transactions, 2015
Recently, it has been a hot topic in the field of medical and disease how to slow down or control the speed of the spread of Ebola. To solve this problem, we divided the whole stage of Ebola spread into three stages: Free-Spread stage, Isolation-Control ...
Y.L. Li, J. Wang, B. Huang, W.X. Liu
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

On the Exact Solution of a Scalar Differential Equation via a Simple Analytical Approach

open access: yesAxioms
The existence of the advance parameter in a scalar differential equation prevents the application of the well-known standard methods used for solving classical ordinary differential equations.
Nada A. M. Alshomrani   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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