Results 131 to 140 of about 227,477 (267)

A multi-grained symmetric differential equation model for learning protein-ligand binding dynamics. [PDF]

Nat Commun
Liu S, Du W, Xu H, Li Y, Li Z, Bhethanabotla V, Yan D, Borgs C, Anandkumar A, Guo H, Chayes J.   +10 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Using an ordinary differential equation model to separate rest and task signals in fMRI. [PDF]

Nat Commun
Kashyap A, Geenjaar E, Bey P, Dhindsa K, Glomb K, Plis S, Keilholz S, Ritter P.   +7 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Ordinary differential equation model of cancer-associated fibroblast heterogeneity predicts treatment outcomes. [PDF]

NPJ Syst Biol Appl
Lee J, Kim E.
europepmc   +1 more source

The effect of state dependence in a delay differential equation model for the El Niño Southern Oscillation. [PDF]

Philos Trans A Math Phys Eng Sci, 2019
Keane A, Krauskopf B, Dijkstra HA.
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Estimating treatment sensitivity in synthetic and in vitro tumors using a random differential equation model. [PDF]

NPJ Syst Biol Appl
Meacham N, Rutter EM.
europepmc   +1 more source

The study on the early warning period of varicella outbreaks based on logistic differential equation model. [PDF]

Epidemiol Infect, 2019
Pang FR, Luo QH, Hong XQ, Wu B, Zhou JH, Zha WT, Lv Y.   +6 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source