Results 61 to 70 of about 227,477 (267)
A generalized differential equation compartmental model of infectious disease transmission
Infectious Disease Modelling, 2021 For decades, mathematical models of disease transmission have provided researchers and public health officials with critical insights into the progression, control, and prevention of disease spread. Of these models, one of the most fundamental is the SIR
Scott Greenhalgh, Carly Rozins
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
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Automatic differentiation and the optimization of differential equation models in biology
Frontiers in Ecology and Evolution, 2022 A computational revolution unleashed the power of artificial neural networks. At the heart of that revolution is automatic differentiation, which calculates the derivative of a performance measure relative to a large number of parameters. Differentiation enhances the discovery of improved performance in large models, an achievement that was previously ...
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Advances in Mathematical Physics, 2021 This article comprehensively and systematically expounds the development trends and basic theory of partial differential methods, analyzes the characteristics of sampling multiscale transformation in detail, and deeply studies the network image denoising
Yang Zhang
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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A Stochastic Differential Equation Inventory Model [PDF]
International Journal of Applied and Computational Mathematics, 2018 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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A Mathematical Model of Epidemics—A Tutorial for Students
Mathematics, 2020 This is a tutorial for the mathematical model of the spread of epidemic diseases. Beginning with the basic mathematics, we introduce the susceptible-infected-recovered (SIR) model.
Yutaka Okabe, Akira Shudo
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