Results 41 to 50 of about 5,148,909 (356)

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

To the boundary value problem of ordinary differential equations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2015
Method for solving of a boundary value problem for ordinary differential equations with boundary conditions at phase and integral constraints is proposed.
Serikbai Aisagaliev, Zhanat Zhunussova
doaj   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Initial-Boundary Value Problems for Anisotropic Parabolic Equations with Variable Exponents of the Nonlinearity in Unbounded Domains with Conditions at Infinity

open access: yesJournal of Optimization, Differential Equations and Their Applications, 2022
We deal with the initial-boundary value problems with some restrictions at infinity for linear and nonlinear anisotropic parabolic second-order equations in unbounded domains with respect to the spatial variables.
Mykola Bokalo
doaj   +1 more source

Solving Ordinary Differential Equations

open access: yesProgramming for Computations - Python, 2019
Differential equations constitute one of the most powerful mathematical tools to understand and predict the behavior of dynamical systems in nature, engineering, and society.
S. Linge, H. Langtangen
semanticscholar   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

Exploring Evolutionary Fitness in Biological Systems Using Machine Learning Methods

open access: yesEntropy, 2020
Here, we propose a computational approach to explore evolutionary fitness in complex biological systems based on empirical data using artificial neural networks. The essence of our approach is the following.
Oleg Kuzenkov   +2 more
doaj   +1 more source

On Disconjugate Differential Equations [PDF]

open access: yesTransactions of the American Mathematical Society, 1968
with continuous coefficients on a t-interval I is said to be disconjugate on I if no solution (0-0) has n zeros on I. For n>2, most known results giving conditions which assure that (0.1) is disconjugate concern perturbations of un -=0 either for a fixed finite interval [as, e.g., in the theorem of de la Vallee Poussin (cf. [2, Exercise 5.3(d), p. 346])
openaire   +2 more sources

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

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