Results 91 to 100 of about 442,456 (299)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Differential Evolution for Multiobjective Portfolio Optimization [PDF]

open access: yes
Financial portfolio optimization is a challenging problem. First, the problem is multiobjective (i.e.: minimize risk and maximize profit) and the objective functions are often multimodal and non smooth (e.g.: value at risk).
Sandra Paterlini, Thiemo Krink
core  

An Algorithm for the Simulations of the Magnetized Neutron Star Cooling

open access: yes, 2015
The model and algorithm for the cooling of the magnetized neutron stars are presented. The cooling evolution described by system of parabolic partial differential equations with non-linear coefficients is solved using Alternating Direction Implicit ...
Ayriyan, A.   +4 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

微分进化多目标优化算法研究

open access: yesJixie chuandong, 2013
Some works are done about the multi-objective differential evolution algorithm and the problems of algorithm in mechanical engineering are revealed.Based on the works,the multi-objective differential evolution algorithm is improved and the constrained ...
钱学毅, 迟建华, 吴双
doaj  

Metaheuristic approach in machinability evaluation of silicon carbide particle/glass fiber–reinforced polymer matrix composites during electrochemical discharge machining process

open access: yesMeasurement + Control, 2019
The advanced manufacturing and machining techniques are adopting a population-based metaheuristic algorithm for production, predicting and decision-making.
Parvesh Antil   +4 more
doaj   +1 more source

A new Algorithm Based on Factorization for Heterogeneous Domain Decomposition [PDF]

open access: yes, 2014
Often computational models are too expensive to be solved in the entire domain of simulation, and a cheaper model would suffice away from the main zone of interest.
Gander, Martin J.   +2 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Comparison of Evolutionary Optimization Algorithms for FM-TV Broadcasting Antenna Array Null Filling [PDF]

open access: yes, 2015
Broadcasting antenna array null filling is a very challenging problem for antenna design optimization. This paper compares five antenna design optimization algorithms (Differential Evolution, Particle Swarm, Taguchi, Invasive Weed, Adaptive Invasive ...
Aristotelis, Bizopoulos   +7 more
core  

Evolutionary optimization of an experimental apparatus

open access: yes, 2013
In recent decades, cold atom experiments have become increasingly complex. While computers control most parameters, optimization is mostly done manually. This is a time-consuming task for a high-dimensional parameter space with unknown correlations. Here
Arlt, J.   +7 more
core   +1 more source

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