Results 91 to 100 of about 2,302,459 (290)

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Geometric Aspects of Mixed Quantum States Inside the Bloch Sphere

open access: yesQuantum Reports
When studying the geometry of quantum states, it is acknowledged that mixed states can be distinguished by infinitely many metrics. Unfortunately, this freedom causes metric-dependent interpretations of physically significant geometric quantities such as
Paul M. Alsing   +3 more
doaj   +1 more source

Discrete differential geometry of fluvial landscapes [PDF]

open access: yesEarth Surface Dynamics
Geomorphology as a discipline is defined by the use of topographic form to understand surface processes on Earth and other planets. In practice this requires drawing connections between quantitative metrics of surface geometry and rates of erosion and ...
N. Klema   +3 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket   +14 more
wiley   +1 more source

Solving p-Laplacian equations on complete manifolds

open access: yesElectronic Journal of Differential Equations, 2006
Using a reduced version of the sub and super-solutions method, we prove that the equation $Delta _{p}u+ku^{p-1}-Ku^{p^{ast }-1}=0$ has a positive solution on a complete Riemannian manifold for appropriate functions $k,K:Mo mathbb{R}$.
Mohammed Benalili, Youssef Maliki
doaj  

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Heat Kernel Embeddings, Differential Geometry and Graph Structure

open access: yesAxioms, 2015
In this paper, we investigate the heat kernel embedding as a route to graph representation. The heat kernel of the graph encapsulates information concerning the distribution of path lengths and, hence, node affinities on the graph; and is found by ...
Hewayda ElGhawalby, Edwin R. Hancock
doaj   +1 more source

Infinitesimal Differential Geometry

open access: yes, 2003
Submitted to: AMUC, December 2003. We added a sheaf property to the definition of $C^n$ space so that now they generalize diffeological spaces and every extended space has now a topology. We also added a final section which compares our construction with other theories of infinitesimals like NSA, SDG and Weil ...
openaire   +3 more sources

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