Results 41 to 50 of about 136,660 (228)

Precise calibration of LIGO test mass actuators using photon radiation pressure

, 1994
Precise calibration of kilometer-scale interferometric gravitational wave detectors is crucial for source localization and waveform reconstruction. A technique that uses the radiation pressure of a power-modulated auxiliary laser to induce calibrated ...
Goetz, E., Kalmus, P., Erickson, S., Savage Jr., R. L., Gonzalez, G., Kawabe, K., Landry, M., Marka, S., O'Reilly, B., Riles, K., Sigg, D., Willems, P.   +11 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Astrometry with the Keck-Interferometer: the ASTRA project and its science

, 2008
The sensitivity and astrometry upgrade ASTRA of the Keck Interferometer is introduced. After a brief overview of the underlying interferometric principles, the technology and concepts of the upgrade are presented.
Andrea M. Ghez, Andrew Cooper, Ben Berkey, Bill Randolph, Boden, Bouchez, Brett Smith, Colavita, Colavita, Colavita, Colette Tyau, Delplancke, Douglas Morrison, Drew Medeiros, Ed Wetherell, Eisner, Eliot Quataert, Esposito, Ghez, Ghez, Gillessen, Gilmozzi, Haniff, James R. Graham, John Monnier, Jorg-Uwe Pott, Josh A. Eisner, Julien Woillez, Kellee Summers, Kevin Tsubota, Labeyrie, Lynne Hillenbrand, Mark M. Colavita, Michael Hrynewych, Monnier, Nevin Weinberg, Peter L. Wizinowich, Pott, Rachel L. Akeson, Rafael Millan-Gabet, Santos, Shao, Tatyana Panteleeva, Vasisht, Weigelt   +44 more
core   +1 more source

From Vision Sensor to Actuators, Spike Based Robot Control through Address-Event-Representation [PDF]

, 2009
One field of the neuroscience is the neuroinformatic whose aim is to develop auto-reconfigurable systems that mimic the human body and brain. In this paper we present a neuro-inspired spike based mobile robot.
Civit Balcells, Antón, Jiménez Fernández, Ángel Francisco, Jiménez Moreno, Gabriel, Linares Barranco, Alejandro, Luján Martínez, Carlos Daniel, Paz Vicente, Rafael   +5 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Computational illumination for high-speed in vitro Fourier ptychographic microscopy [PDF]

, 2015
We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or high resolution,
Chen, Michael, Liu, Ziji, Tian, Lei, Waller, Laura, Yeh, Li-Hao, Zhong, Jingshan   +5 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Investigating viscous damping using a webcam

, 2011
We describe an experiment involving a mass oscillating in a viscous fluid and analyze viscous damping of harmonic motion. The mechanical oscillator is tracked using a simple webcam and an image processing algorithm records the position of the geometrical
Anwar, Muhammad Sabieh, Shamim, Sohaib, Zia, Wasif   +2 more
core   +1 more source