Results 151 to 160 of about 1,349,398 (291)

Epidermal inclusion cyst of the breast: A case report. [PDF]

Radiol Case Rep
Vásquez-Rentería PD, Claure-Robles DD, Grados-Godenzi DA, Coronel-Arias S.   +3 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

On the solutions of a coupled system of proportional fractional differential inclusions of Hilfer type

Modern Mathematical Methods
A multi-point and integro-multi-strip boundary value problem associated to a Hilfer type coupled system of fractional differential inclusions is studied. The existence of solutions is established in the case when the set-valued maps has nonconvex values.
Aurelian Cernea
doaj  

Interdependent Regulation of Alternative Splicing by Serine/Arginine-Rich and Heterogeneous Nuclear Ribonucleoprotein Splicing Factors. [PDF]

Genes (Basel)
Holmes ME, Hertel KJ.
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

SNRPD2-mediated regulation of DDX39B splicing promotes endometrial cancer progression by suppressing the activation of CTSC cryptic exons. [PDF]

Cell Death Dis
Li Y, Chen Z, Liu Y, Gao Y, Pu Y, Gao Q, Gao F, Yang N, Li P.   +8 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Separate transcription and splicing gene networks are linked and coordinated by the pRb-E2F pathway. [PDF]

Nucleic Acids Res
Carr SM, Liu G, Barczak W, Syffudin H, Munro S, Reyna-Jeldes D, Vendrell I, Kessler B, Cribbs AP, Kanapin A, Samsonova A, La Thangue NB.   +11 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Exon inclusion signatures enable accurate estimation of splicing factor activity. [PDF]

Nat Commun
Anglada-Girotto M, Segura-Morales C, Moakley DF, Zhang C, Miravet-Verde S, Califano A, Serrano L.   +6 more
europepmc   +1 more source