Results 151 to 160 of about 3,146,217 (305)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Asynchronous stochastic approximation with differential inclusions
The asymptotic pseudo-trajectory approach to stochastic approximation of Benaïm, Hofbauer and Sorin is extended for asynchronous stochastic approximations with a set-valued mean field.
David S. Leslie, Steven Perkins
doaj
Senior teacher perceptions towards inclusion [PDF]
Plan BResearch has been conducted on the perceptions that teachers have towards the inclusion of students with disabilities into the regular education classroom.
Larson, Shawna A.
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Two solutions for fractional p-Laplacian inclusions under nonresonance
We study a pseudo-differential inclusion driven by the fractional p-Laplacian operator and involving a nonsmooth potential, which satisfies nonresonance conditions both at the origin and at infinity.
Antonio Iannizzotto +2 more
doaj
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
On a system involving an integro-differential inclusion with subdifferential and caputo fractional derivative [PDF]
The current work is concerned with a new system involving an integro-differential inclusion of subdifferential type and Caputo fractional derivative, in Hilbert spaces.
Bouabsa, Aya, Saidi, Soumia
core
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

