Results 201 to 210 of about 32,198 (263)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Cytomegalovirus Lymphadenitis After Anti-CD19 Chimeric Antigen Receptor T-cell (CAR-T): An Underappreciated Etiology of Hypermetabolic Lymphadenopathy in the Post-CAR-T Setting. [PDF]

Cureus
Rosas D, Cox A, Martinez D, Fares A, Ouansafi I, Melendez D, Sandoval-Sus J.   +6 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Analysis of Cytomegalovirus Infection Affecting the Stomach. [PDF]

Gastroenterol Res Pract
Diao Y, Zong Y, Xu R, Chen G, Yang X, Zhao H.   +5 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Autopsy-Confirmed CMV Adrenalitis With Bilateral Adrenal Hemorrhage Following Presumed Critical Illness-Related Corticosteroid Insufficiency During Prolonged ICU Stay: A Case Report. [PDF]

Case Rep Crit Care
Kanamitsu Y, Seino Y, Toyoda N, Sugiura Y, Takano T, Kunishima H, Sato Y, Izumo M, Fujitani S.   +8 more
europepmc   +1 more source

Physics-Guided Deep Learning for Interpretable Biomedical Image Reconstruction and Pattern Recognition in Diagnostic Frameworks. [PDF]

Bioengineering (Basel)
Qadir A, Arif S, Valsalan P, Khan O.
europepmc   +1 more source

ASO therapy rescues NOTCH2NLC GGC repeat expansion-induced genomic damage, 3D chromatin structural abnormalities, and senescence. [PDF]

Nat Commun
Li M, Tang M, Hao X, Hu Z, Ma D, Li S, Zuo C, Wang Z, Liang Y, Feng Y, Hao C, Wang C, Li H, Yang Y, Sun Y, Qi S, Mao C, Xu Y, Wang Q, Yang, Yang R, Zhou Z, Ji P, Tan S, Zhang Z, Chen H, La Spada AR, Shi C.   +27 more
europepmc   +1 more source

Molecular signatures and biomarker development for limbic-predominant age-related TDP-43 encephalopathy (LATE). [PDF]

Acta Neuropathol
Wu L, Akingbade T, Nelson PT, Wang SJ, Xu B.   +4 more
europepmc   +1 more source

Nuclear Medicine Imaging Biomarkers in Parkinson's Disease: Past, Present, and Future Directions. [PDF]

Med Sci (Basel)
Martini AL, Sestini S, Guarino DS, Feraco P.   +3 more
europepmc   +1 more source