Results 71 to 80 of about 36,261 (305)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Extremal Solutions of Functional Differential Inclusions [PDF]

open access: yes, 1993
In this paper, we prove the existence of extremal solutions of functional differential inclusions, in particular, we can prove the existence of extremal solutions of differential inclusions without assuming that the right-hand side multifunction is ...
Hu, S.C.   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

PROPERTIES OF OPTIMAL SETS OF PRACTICAL STABILITY OF DIFFERENTIAL INCLUSIONS. Part I. Part II

open access: yesМіжнародний науково-технічний журнал "Проблеми керування та інформатики", 2006
In this paper we define four types of practical stability of differential inclusions and propose the properties of the maximum set of initial conditions of these types of practical stability. We give the main results in practical stability estimation of
F.G. Garashchenko, V.V. Pichkur
doaj  

Delay differential inclusions with constraints [PDF]

open access: yesProceedings of the American Mathematical Society, 1995
In this paper we examine functional differential inclusions with memory and state constraints. For the case of time-independent state constraints, we show that the solution set is
Hu, Shouchuan, Papageorgiou, Nikolaos S.
openaire   +2 more sources

Periodic solutions for differential inclusions in ${\Bbb R}^N$ [PDF]

open access: yes, 2006
summary:We consider first order periodic differential inclusions in $\mathbb {R}^N$. The presence of a subdifferential term incorporates in our framework differential variational inequalities in $\mathbb {R}^N$.
Papageorgiou, Nikolaos S.   +1 more
core  

Controllability of Neutral Impulsive Differential Inclusions with Non-Local Conditions [PDF]

open access: yes, 2011
In this short article, we have studied the controllability result for neutral impulsive differential inclusions with nonlocal conditions by using the fixed point theorem for condensing multi-valued map due to Martelli [1].
Chalishajar, Dimplekumar N.; Acharya, Falguni S.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Discretization methods for nonconvex differential inclusions

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2009
We prove the existence of solutions for the differential inclusion $\dot x(t)\in F(t,x(t)) + f(t,x(t))$ for a multifunction $F$ upper semicontinuous with compact values contained in the generalized Clarke gradient of a regular locally Lipschitz function ...
M. Yarou
doaj   +1 more source

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