Results 41 to 50 of about 9,343 (207)

Stress Interference in Axisymmetric Torsion of a Transeversely Isotropic Body [PDF]

, 1985
An unbounded transversely isotropic body of revolution containing two spheroidal cavities is subjected to torsion about its axis of elastic symmetry, which coincides with its axis of revolution.
Eubanks, R.A., Heinrich, Stephen Michael
core  

Constructing and exploring wells of energy landscapes

, 2004
Landscape paradigm is ubiquitous in physics and other natural sciences, but it has to be supplemented with both quantitative and qualitatively meaningful tools for analyzing the topography of a given landscape.
Annick Lesne, Attouch H., Aubin J.-P., Aubin J.-P., Aubin J.-P., Aubin J.-P., Aubin J.-P., Frenkel D., Jean-Pierre Aubin, Kauffman S. A., Laguës M., Mézard M., Saint-Pierre P.   +12 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Growth-Induced In-Plane Uniaxial Anisotropy in V$_{2}$O$_{3}$/Ni Films

, 2017
We report on a strain-induced and temperature dependent uniaxial anisotropy in V$_{2}$O$_{3}$/Ni hybrid thin films, manifested through the interfacial strain and sample microstructure, and its consequences on the angular dependent magnetization reversal.
de la Venta, Jose, Gilbert, Dustin A., Liu, Kai, Ramírez, Juan Gabriel, Saerbeck, Thomas, Schuller, Ivan K., Trastoy, Juan   +6 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Nonequilibrium 1/f Noise in Low-doped Manganite Single Crystals

, 2007
1/f noise in current biased La0.82Ca0.18MnO3 crystals has been investigated. The temperature dependence of the noise follows the resistivity changes with temperature suggesting that resistivity fluctuations constitute a fixed fraction of the total ...
B. Dolgin, G. Jung, Glazman L. I., M. Belogolovskii, V. Markovich, X. D. Wu, Y. Yuzhelevski, Ya. M. Mukovskii   +7 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A perspective from extinct radionuclides on a Young Stellar Object: The Sun and its accretion disk

, 2011
Meteorites, which are remnants of solar system formation, provide a direct glimpse into the dynamics and evolution of a young stellar object (YSO), namely our Sun.
Christophe Michel-Lévy M, Das JP, Dauphas N, Grimm RE, Hollenbach DJ, Hudson GB, Hutcheon ID, Jacobsen B, Kita NT, Kleine T, MacPherson GJ, Marc Chaussidon, Mostéfaoui S, Nagashima K, Nagashima K, Nicolas Dauphas, Safronov VS, Tang H, Wetherill GW., Wetherill GW., Yin Q-Z   +20 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source