Results 61 to 70 of about 1,453,219 (150)

Demonstration of SAR Interferometry under Crossing Orbits using TerraSAR-X and TanDEM-X [PDF]

, 2011
This paper discusses cross-track SAR interferometry under crossing orbits. The underlaying theory is briefly outlined, showing that a crossing angle between the ground tracks needs to be compensated by applying different squint angles in order to ...
Wollstadt, Steffen, Paco Lopez-Dekker, Francesco De Zan, Pau Prats, Krieger, Gerhard, Daniel Schulze, Schulze, Daniel, De Zan, Francesco, Alberto Moreira, López-Dekker, Paco, Moreira, Alberto, Steffen Wollstadt, Prats, Pau, Gerhard Krieger   +13 more
core   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Bioinspired Metastable Transient Peeling for Repeatable Rapid Release

Advanced Science, EarlyView.
Inspired by the explosive seed ejection of the squirting cucumber, this work introduces metastable transient peeling that temporally regulates stored interfacial energy release via a tunable energy barrier. A viscoelastic hemispherical gripper achieves 52 ms ultrafast, residue‐free release with 300 000‐cycle durability, enabling damage‐free handling of
Lvzhou Li, Qingyue Li, Yao Hu, Xu Dong, Xiangli Wen, Kai Zhu, Yaoyao Jiang, Yu Tian, Jianning Ding   +8 more
wiley   +1 more source

Acceleration computing process in wavelength scanning interferometry [PDF]

, 2011
The optical interferometry has been widely explored for surface measurement due to the advantages of non-contact and high accuracy interrogation. Eventually, some interferometers are used to measure both rough and smooth surfaces such as white light ...
Gao, F., Muhamedsalih, Hussam, Jiang, Xiang   +2 more
core   +2 more sources

Differential Interferometry Applications

, 2011
Differential Interferometry Applications 1) High Resolution Interferometry with TerraSAR-X 2) Wide Area Persistent Scatterer ...
Parizzi, Alessandro, Adam, Nico, Rodriguez Gonzalez, Fernando   +2 more
core  

A Bayesian Method for Very High Resolution Multi Aspect Angle Radargrammetry [PDF]

, 2010
InSAR’s capabilities have been considerably improved by advanced processing techniques such as Persistent Scatterer Interferometry (PSI) and SAR Tomography (TomoSAR). However, complicated scattering situations (e.g. layover) need to be better resolved in
Goel, Kanika, Adam, Nico Alexander
core  

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Lab‐Scale Fabrication Process Selection for Soft Robotics: Benchmarking, Tradeoffs, and Guidelines for Formative Manufacturing of Soft Silicone Components

Advanced Intelligent Systems, EarlyView.
Fabrication shapes soft robot performance, but benchmarking data and selection guidelines remain scarce. We fabricate silicone actuators using two molding techniques and three mold types, characterizing them with cycle testing, microscopy, profilometry, and 3D imaging. Applying our lab‐scale, soft robotics‐specific fabrication evaluation criteria shows
Charlotte M. Folinus, Daniel Massimino, Cat Arase, Kaitlyn P. Becker   +3 more
wiley   +1 more source