Results 201 to 210 of about 230,628 (307)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Measurement invariance and differential item functioning of the positive and negative affect schedule: a psychometric study in Ecuadorian young adults. [PDF]

Front Psychol
Parra-Gaete C, Vinueza-Cabezas A, Bourgeat-Salazar M.   +2 more
europepmc   +1 more source

Generalized Mantel-Haenszel Estimators for Simultaneous Differential Item Functioning Tests. [PDF]

Educ Psychol Meas, 2023
Liu I, Suesse T, Harvey S, Gu PY, Fernández D, Randal J.   +5 more
europepmc   +1 more source

When can Multidimensional Item Response Theory (MIRT) Models be a Solution for Differential Item Functioning (DIF)? A Monte Carlo Simulation Study

, 2015
Yuan‐Ling Liaw
openalex   +1 more source

Advantages of Spike and Slab Priors for Detecting Differential Item Functioning Relative to Other Bayesian Regularizing Priors and Frequentist Lasso

, 2021
Siyuan Marco Chen, Daniel J. Bauer, William C. M. Belzak, Holger Brandt   +3 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Performance differences with and without differential item functioning in the post graduate admission test in Saudi Arabia based on gender and ability level. [PDF]

Front Psychol
Darandari EZ, Almeri MA.
europepmc   +1 more source

The tendency to avoid physical activity and sport scale (TAPAS): Rasch analysis with differential item functioning testing among a Chinese sample. [PDF]

BMC Psychol, 2023
Fan CW, Chang YL, Huang PC, Fung XCC, Chen JK, Bevan N, O'Brien KS, Yeh YC, Chen HP, Chen IH, Lin IC, Griffiths MD, Lin CY.   +12 more
europepmc   +1 more source

Recent advances in analysis of differential item functioning in health research using the Rasch model [PDF]

, 2017
Curt Hagquist, David Andrich
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source