Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Measurement invariance and differential item functioning of the positive and negative affect schedule: a psychometric study in Ecuadorian young adults. [PDF]
Parra-Gaete C +2 more
europepmc +1 more source
Generalized Mantel-Haenszel Estimators for Simultaneous Differential Item Functioning Tests. [PDF]
Liu I +5 more
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Performance differences with and without differential item functioning in the post graduate admission test in Saudi Arabia based on gender and ability level. [PDF]
Darandari EZ, Almeri MA.
europepmc +1 more source
The tendency to avoid physical activity and sport scale (TAPAS): Rasch analysis with differential item functioning testing among a Chinese sample. [PDF]
Fan CW +12 more
europepmc +1 more source
Recent advances in analysis of differential item functioning in health research using the Rasch model [PDF]
Curt Hagquist, David Andrich
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source

