Results 261 to 270 of about 656,712 (390)

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Rasch analysis of the self efficacy (SE-12) questionnaire measuring clinical communication skills

open access: yesPEC Innovation
Objective: The aim of this study was to examine the construct validity and reliability of the Self Efficacy (SE-12) questionnaire using Rasch analysis. Methods: The SE-12 was administered to Danish health care professionals prior to their participation ...
Kaj Sparle Christensen, Jette Ammentorp
doaj  

Reevaluating the SIBTEST Classification Heuristics for Dichotomous Differential Item Functioning. [PDF]

open access: yesEduc Psychol Meas, 2022
Weese JD   +4 more
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Differential item functioning of the revised Multigroup Ethnic Identity Measure (MEIM-R) in racially and income diverse youth with type 1 diabetes. [PDF]

open access: yesJ Pediatr Psychol
Choquette AE   +14 more
europepmc   +1 more source

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