Results 111 to 120 of about 81,501 (296)

Animacy-based grammatical asymmetries in Basque: a typological perspective

Anuario del Seminario de Filología Vasca "Julio de Urquijo", 2018
This study provides a typological analysis of two phenomena related to case-marking in Basque. In both of them, animacy —or the distinction between what is animate and what is not— turns out to be determinant: we discuss case assignment to direct objects,
Iván Igartua, Ekaitz Santazilia
doaj  

Differential Object Marking in Ancient Greek [PDF]

Linguistics, 2014
Peer ...
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Quantization of Hitchin integrable system via positive characteristic

, 2016
In a celebrated unpublished manuscript Beilinson and Drinfeld quantize the Hitchin integrable system by showing that the global sections of critically twisted differential operators on the moduli stack of G-bundles on an algebraic curve is identified ...
Bezrukavnikov, Roman, Chen, Tsao-Hsien, Travkin, Roman, Zhu, Xinwen   +3 more
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

The Spanish impersonal se-construction. Constructional variation and change

Constructions, 2005
The aim of this paper is to analyze, synchronically and diachronically, aspects of the Spanish impersonal se-construction that have not yet been satisfactorily accounted for in Spanish linguistics.
Johan Pedersen
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Variable Acceptability of Differential Object Marking in Bilingual Galician–Spanish Speakers: An Exploratory Study

Languages
This paper presents an initial study of the acceptability of differential object marking (DOM) by Galician–Spanish bilinguals in Galicia. The research explores judgments provided by these bilinguals (n = 69) on DOM in both Galician and Spanish and it ...
Manuel Delicado Cantero, M. Carmen Parafita Couto   +1 more
doaj   +1 more source

Specificity and definiteness in sentence and discourse structure [PDF]

, 2013
In this paper, I argue that this informally given list of characteristics covers only a certain subclass of specific indefinites. […] In particular, I dispute the definition of specific indefinites as "the speaker has the referent in mind" as rather ...
Heusinger, Klaus von
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source