Results 111 to 120 of about 81,557 (295)
Animacy-based grammatical asymmetries in Basque: a typological perspective
Anuario del Seminario de Filología Vasca "Julio de Urquijo", 2018 This study provides a typological analysis of two phenomena related to case-marking in Basque. In both of them, animacy —or the distinction between what is animate and what is not— turns out to be determinant: we discuss case assignment to direct objects,
Iván Igartua, Ekaitz Santazilia
doaj
Differential Object Marking in Ancient Greek [PDF]
Linguistics, 2014 Peer ...
openaire +2 more sources
Quantization of Hitchin integrable system via positive characteristic
, 2016 In a celebrated unpublished manuscript Beilinson and Drinfeld quantize the Hitchin integrable system by showing that the global sections of critically twisted differential operators on the moduli stack of G-bundles on an algebraic curve is identified ...
Bezrukavnikov, Roman +3 more
core
Specificity and definiteness in sentence and discourse structure [PDF]
, 2013 In this paper, I argue that this informally given list of characteristics covers only a certain subclass of specific indefinites. […] In particular, I dispute the definition of specific indefinites as "the speaker has the referent in mind" as rather ...
Heusinger, Klaus von
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Spanish impersonal se-construction. Constructional variation and change
Constructions, 2005 The aim of this paper is to analyze, synchronically and diachronically, aspects of the Spanish impersonal se-construction that have not yet been satisfactorily accounted for in Spanish linguistics.
Johan Pedersen
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
LanguagesThis paper presents an initial study of the acceptability of differential object marking (DOM) by Galician–Spanish bilinguals in Galicia. The research explores judgments provided by these bilinguals (n = 69) on DOM in both Galician and Spanish and it ...
Manuel Delicado Cantero +1 more
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source