Results 111 to 120 of about 3,562,253 (279)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Balkan Romance and Southern Italo-Romance: Differential Object Marking and Its Variation

Languages
The main goal of this article is to examine in detail an area of the grammar where standard Romanian, a Balkan Sprachbund language of the Romance phylum, and the Romance dialects of Southern Italy (here we used the dialect of Ragusa, in South-East Sicily)
Monica Alexandrina Irimia, Cristina Guardiano   +1 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The Spanish impersonal se-construction. Constructional variation and change

Constructions, 2005
The aim of this paper is to analyze, synchronically and diachronically, aspects of the Spanish impersonal se-construction that have not yet been satisfactorily accounted for in Spanish linguistics.
Johan Pedersen
doaj  

Are we making progress in understanding differential object marking?

, 2018
The topic of differential object marking (DOM), or more broadly differential argument marking, continues to be popular in different circles. The journal Linguistics had a special issue in 2014 with 11 papers, there is a recent LangSci volume on the ...
Martin Haspelmath
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Variable Acceptability of Differential Object Marking in Bilingual Galician–Spanish Speakers: An Exploratory Study

Languages
This paper presents an initial study of the acceptability of differential object marking (DOM) by Galician–Spanish bilinguals in Galicia. The research explores judgments provided by these bilinguals (n = 69) on DOM in both Galician and Spanish and it ...
Manuel Delicado Cantero, M. Carmen Parafita Couto   +1 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Task Type and Distributional Differences in the Spanish Differential Object Marking of Catalan–Spanish Bilinguals

Languages
This study examines offline acceptance and online processing of Differential Object Marking (DOM) in the Spanish of Catalan–Spanish bilinguals in Catalonia. Both languages evidence DOM, though prescriptive grammars claim only partial overlap.
Tiffany Judy, Eloi Puig-Mayenco
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source