Results 61 to 70 of about 224 (165)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Towards an account of differential object marking in romanian
Bucharest Working Papers in Linguistics, 2010 This paper proposes an analysis of Differential Object Marking in present-day Romanian along the lines of the DRT framework put forth by Kamp and Reyle (1993) and developed by Farkas and de Swart (2001), Farkas (2002), and Farkas and Heusinger (2003). We
Alina Tigău
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Partitivity and case marking in Turkish and related languages
Glossa, 2017 The paper discusses the conditions for case marking on partitive constructions in direct object position in Turkish and some related languages. We focus on Turkish and then turn to some details of corresponding constructions in some other Turkic ...
Jaklin Kornfilt, Klaus von Heusinger
doaj +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Argument Strength and Differential Case Marking: Some Evidence from Hawrami [PDF]
مطالعات زبانها و گویشهای غرب ایران, 2013 Differential Case Marking (DCM) refers to a situation in which only some nominals with a specific grammatical function are overtly case-marked and others remain unmarked.
Mohammad Rasekh Mahand +1 more
doaj
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Anuario del Seminario de Filología Vasca "Julio de Urquijo", 2018 This study provides a typological analysis of two phenomena related to case-marking in Basque. In both of them, animacy —or the distinction between what is animate and what is not— turns out to be determinant: we discuss case assignment to direct objects,
Iván Igartua, Ekaitz Santazilia
doaj
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source