Results 111 to 120 of about 1,878,592 (297)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Thirty-first Illinois Custom Spray Operators Training School: summaries of presentations [PDF]

, 1979
Made available in DSpace on 2016-03-17T21:24:49Z (GMT). No. of bitstreams: 2 749322_1979.pdf: 25608937 bytes, checksum: a190a7b2270aef124526f80493eb0a69 (MD5) license.txt: 4846 bytes, checksum: 927d59ba442de31571446841df3d90ca (MD5) Previous issue date:
Illinois Custom Spray Operators' School
core  

The Cauchy problem for the Navier-Stokes equations

Қарағанды университетінің хабаршысы. Математика сериясы, 2020
In the paper we study issues of a strong solution for "essentially" loaded differential equations of the parabolic type in bounded domains. Features of the problems under consideration: for example, in the L 2( Q ) space the corresponding differential ...
A.Sh. Akysh (Akishev)
doaj  

Mathematical model of Ebola and Covid-19 with fractional differential operators: Non-Markovian process and class for virus pathogen in the environment. [PDF]

Chaos Solitons Fractals, 2020
Zhang Z, Jain S.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

On boundary value problems for essentially loaded parabolic equations in bounded domains

Қарағанды университетінің хабаршысы. Математика сериясы, 2020
In the paper we study issues of a strong solution for "essentially" loaded differential equations of the parabolic type in bounded domains. Features of the problems under consideration: for example, in the L 2( Q ) space the corresponding differential ...
D.M. Akhmanova, N.K. Shamatayeva, L.Zh. Kasymova   +2 more
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Twenty-eighth Illinois Custom Spray Operators' Training School: summaries of presentations [PDF]

, 1976
Made available in DSpace on 2016-03-17T21:24:46Z (GMT). No. of bitstreams: 2 749322_1976.pdf: 26589794 bytes, checksum: c1ff1cdfd0fd85c1cb6b4f7646d0d1aa (MD5) license.txt: 4846 bytes, checksum: 927d59ba442de31571446841df3d90ca (MD5) Previous issue date:
Illinois Custom Spray Operators' School
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