Results 51 to 60 of about 1,878,592 (297)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Symbolic Analysis for Boundary Problems: From Rewriting to Parametrized Groebner Bases [PDF]
We review our algebraic framework for linear boundary problems (concentrating on ordinary differential equations). Its starting point is an appropriate algebraization of the domain of functions, which we have named integro-differential algebras.
Regensburger, Georg +4 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
On weighted positivity of ordinary differential operators
Some elliptic differential operators possess a weighted positivity property, where the weight is a fundamental solution of the operator. This property has interesting applications to partial differential operators.
Eilertsen Stefan
doaj
Differential operators on orbifolds
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Natural and Projectively Invariant Quantizations on Supermanifolds
The existence of a natural and projectively invariant quantization in the sense of P. Lecomte [Progr. Theoret. Phys. Suppl. (2001), no. 144, 125-132] was proved by M. Bordemann [math.DG/0208171], using the framework of Thomas-Whitehead connections.
Thomas Leuther, Fabian Radoux
doaj +1 more source
Geometry of differential operators and odd Laplace operators [PDF]
We solve the following problem: to describe in geometric terms all differential operators of the second order with a given principal symbol. Initially the operators act on scalar functions. Operator pencils acting on densities of arbitrary weights appear naturally in the course of study.
Voronov, F. F., Khudaverdyan, O. M.
openaire +2 more sources
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source

