Results 61 to 70 of about 254,345 (274)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Trajectory differential privacy protection mechanism based on prediction and sliding window

Tongxin xuebao, 2020
To address the issues of privacy budget and quality of service in trajectory differential privacy protection,a trajectory differential privacy mechanism integrating prediction disturbance was proposed.Firstly,Markov chain and exponential perturbation ...
Ayong YE, Lingyu MENG, Ziwen ZHAO, Yiqing DIAO, Jiaomei ZHANG   +4 more
doaj   +2 more sources

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Goodness-of-Fit Testing for Hölder Continuous Densities Under Local Differential Privacy [PDF]

, 2023
Amandine Dubois, Thomas B. Berrett, Cristina Butucea   +2 more
openalex   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Reconstruction Attacks on Aggressive Relaxations of Differential Privacy

The Journal of Privacy and Confidentiality
Differential privacy is a widely accepted formal privacy definition that allows aggregate information about a dataset to be released while controlling privacy leakage for individuals whose records appear in the data.
Prottay Protivash, John Durrell, Daniel Kifer, Zeyu Ding, Danfeng Zhang   +4 more
doaj   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source

Privacy Auditing in Differential Private Machine Learning: The Current Trends

Applied Sciences
Differential privacy has recently gained prominence, especially in the context of private machine learning. While the definition of differential privacy makes it possible to provably limit the amount of information leaked by an algorithm, practical ...
Ivars Namatevs, Kaspars Sudars, Arturs Nikulins, Kaspars Ozols   +3 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Local Differential Privacy Location Protection for Mobile Terminals Based on Huffman Coding [PDF]

Jisuanji kexue yu tansuo
The location information of mobile terminals is closely linked to personal privacy, which may threaten users’ life and property safety if leaked. Local differential privacy model provides strict privacy protection effect, allows users to handle and ...
YAN Yan, LYU Yaqin, LI Feifei
doaj   +1 more source