Results 191 to 200 of about 28,711 (238)

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Somatic gene repression ensures physical segregation of germline and soma in Drosophila embryos. [PDF]

EMBO Rep
Asaoka M, Kayama M, Kawagoe T, Hayashi M, Morita S, Kobayashi S.   +5 more
europepmc   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Landscape of Somatic and Age-Related Pathogenic Structural Variations in Hepatocellular Carcinoma Revealed by Long-Read Sequencing. [PDF]

MedComm (2020)
Wei Z, Cao Y, Liu H, Liu M, Zhang B, Ying J, Cai J, Bi X, Zhao J, Zhou J, Li Z, Huang Z, Liu J, Lv X, Luo Z, Wei Z, Zhang X, Yang Y, Deng Y, Yin Y, Chen J, Liang J, Wang X, Zhang Y, Zhao H.   +24 more
europepmc   +1 more source

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

Advanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi, Ana Rosu, Shreyas Kuddannaya, Gautier Laurent, Rana Bazzi, Stéphane Roux, Ali Shakeri‐Zadeh, Jeff W. M. Bulte   +7 more
wiley   +1 more source

Lenalidomide-associated reversible TP53-mutated clonal hematopoiesis in plasma cell neoplasms. [PDF]

Haematologica
Gocke CB, Peters M, Gocke CD, Ali SA, Huff CA, Imus PH, DeZern AE, Gondek LP.   +7 more
europepmc   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

In Materia Shaping of Randomness with a Standard Complementary Metal‐Oxide‐Semiconductor Transistor for Task‐Adaptive Entropy Generation

Advanced Functional Materials, EarlyView.
This study establishes a materials‐driven framework for entropy generation within standard CMOS technology. By electrically rebalancing gate‐oxide traps and Si‐channel defects in foundry‐fabricated FDSOI transistors, the work realizes in‐materia control of temporal correlation – achieving task adaptive entropy optimization for reinforcement learning ...
Been Kwak, Ryun‐Han Koo, Youngchan Cho, Changhyeon Han, Dongbin Kim, Soi Jeong, Yunho Shin, Joonhyeok Choi, Jiseong Im, Jonghyun Ko, Jong‐Ho Lee, Jangsaeng Kim, Youngho Kang, Wonjun Shin, Daewoong Kwon   +14 more
wiley   +1 more source

Triple-negative primary myelofibrosis: a comparative analysis of phenotype, genotype, and outcome. [PDF]

Blood Cancer J
Bashir YA, Abdelrheem AA, Abdelmagid M, Reichard KK, He R, Zepeda Mendoza CJ, Pardanani A, Gangat N, Tefferi A.   +8 more
europepmc   +1 more source

Spatially Tailorable Liquid Crystalline Elastomer Alignment During Digital Light Process 3D Printing

Advanced Functional Materials, EarlyView.
Here, we report the fabrication of 3D printable liquid crystalline elastomer (LCE) structures with spatially tailorable alignment domains within the same layer. This work addresses the long‐standing challenge of preparing complex 3D LCE architectures with patterned functional domains to achieve nonlinear deformations. Fabrication of multi‐domains in 3D
Adam Bischoff, Saman Jamshididana, Zach Miller, Kassandra Hernandez, Nicolas Gonsalves, Andre Olarra, Elliot Yoo, Jeremy A. Herman, Devin J. Roach   +8 more
wiley   +1 more source