Results 251 to 260 of about 340,748 (309)

Whole genome sequencing and single-cell transcriptomics identify KMT2D inactivation as a potential new driver for pituitary tumors: a case report. [PDF]

BJC Rep
Brunner M, Meylan-Merlini J, Muriset M, Oreshkov S, Messina A, Messerer M, Daniel R, Hewer E, Brouland JP, Santoni F.   +9 more
europepmc   +1 more source

Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani, Ashley R. Johnson, Akmal H. Sabri, Ryan Lutz, Steven Tignor, Jeanine Ballard, Nathan Rudd, Li Zhao, Lalitkumar K. Vora, Stephanie E. Barrett, Angela Wagner, Ryan F. Donnelly   +11 more
wiley   +1 more source

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

Advanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li, Andi Dian Permana, Juan Domínguez‐Robles, Muh Nur Amir, Habibie Habibie, Qonita Kurnia Anjani, Li Zhao, Natalia Moreno‐Castellanos, Ryan F Donnelly, Eneko Larrañeta   +9 more
wiley   +1 more source

Lymphocyte signatures correspond to clinical phenotypes in autoimmune limbic encephalitis. [PDF]

Brain Commun
Räuber S, Schulte-Mecklenbeck A, Sarink K, Müller C, Mannil M, Langenbruch L, Dik A, Barman S, Strippel C, Gallus M, Golombeck KS, Schroeter CB, Willison A, Nelke C, Ismail FS, Schwindt W, Goebels N, Kovac S, Wiendl H, Meyer Zu Hörste G, Duning T, Hanke M, Ruck T, Heindel W, Dannlowski U, Hahn T, Gross CC, Meuth SG, Melzer N.   +28 more
europepmc   +1 more source

Use of Total and Differential Somatic Cell Counts to Differentiate Potentially Infected from Potentially Non-infected Quarters and Cows and Between Herds of Various Levels of Infection

, 1980
A H Meek, D. A. Barnum, F. H. S. Newbould   +2 more
openalex   +1 more source

Longer Acting Injectable: Continuous, Linear Release of a Progestin Contraceptive From an Oxidized Porous Silicon Host

Advanced Healthcare Materials, EarlyView.
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett, Ruhan Fan, Tushar Kumeria, Heidi Leonard, Byungji Kim, Taylor R. Martin, Irmak Ipekci, Joanna Wang, Jiuk Byun, Nicole A. Chan, Amber Pierron, Curtis E. Moore, Jennifer Ayres, Michael J. Sailor   +13 more
wiley   +1 more source

Impact of a teat disinfectant based on Lactococcus cremoris on the cow milk proteome. [PDF]

BMC Vet Res
Addis MF, Maffioli EM, Gazzola A, Santandrea F, Tedeschi G, Piccinini R.   +5 more
europepmc   +1 more source

Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa, Ana Marote, Catarina Barbosa, Jonas Campos, António J. Salgado, Jana B. Nieder   +5 more
wiley   +1 more source

Effect of Dietary Addition of <i>Lentinus edodes</i> on Rumen Flora, Lactation, and Health of Dairy Goats. [PDF]

Animals (Basel)
Shen H, Wang M, Ning Y, Zhao Y, Danzeng B, Li K, Shi H, Li W.   +7 more
europepmc   +1 more source

Mechanically and Chemically Defined PEG Hydrogels Improve Reproducibility in Human Cardioid Development

Advanced Healthcare Materials, EarlyView.
Synthetic matrix metalloproteinase (MMP)‐degradable polyethylene glycol (PEG)‐based hydrogels are developed to investigate the influence of mechanical and biochemical cues on cardioid development. Matrix stiffness and cell adhesion motifs significantly regulate cardioid formation, chamber morphogenesis, contractile function, and cardioid transcriptome.
Yuanhui Song, Michael Seitz, Andrew Kowalczewski, Nhu Y Mai, Era Jain, Huaxiao Yang, Zhen Ma   +6 more
wiley   +1 more source