Results 111 to 120 of about 663,265 (283)

The Use of Sumudu Transform for Solving Certain Nonlinear Fractional Heat-Like Equations

Abstract and Applied Analysis, 2013
We make use of the properties of the Sumudu transform to solve nonlinear fractional partial differential equations describing heat-like equation with variable coefficients.
Abdon Atangana, Adem Kılıçman
doaj   +1 more source

The general form of the Euler--Poisson--Darboux equation and application of transmutation method

, 2017
In the paper we find solution representations in the compact integral form to the Cauchy problem for a general form of the Euler--Poisson--Darboux equation with Bessel operators via generalized translation and spherical mean operators for all values of ...
Shishkina, Elina L., Sitnik, Sergei M.
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

SERIES SOLUTION OF TYPHOID FEVER MODEL USING DIFFERENTIAL TRANSFORM METHOD

Malaysian Journal of Computing, 2018
This paper presents an analysis of PSIuIeTR type model, which are used to study the transmission dynamics of typhoid fever diseases in a population. Basic idea of typhoid fever disease transmission using compartmental modeling is discussed.
O. J. Peter, O. B. Akinduko, C. Y. Ishola , O. A. Afolabi , A. B. Ganiyu
doaj   +1 more source

Nonlinear Differential Equations and Mixture of Tarig Transform and Differential Transform Method

, 2015
In this paper, we apply a new integral transform ''Tarig transform'' with the differential transform method to solve some nonlinear differential equations .The method is based on Tarig transform and differential transform methods. The nonlinear terms can be easily handled by the use of differential transform method.
openaire   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Numerical investigation of fractional Fisher partial differential equation via natural transform decomposition method

Partial Differential Equations in Applied Mathematics
In modern Science, a Fisher non-linear differential equation plays a significant role due to its diverse applications in fisher hypothesis, mathematical biology, engineering, physics and ecology. In this regard, the authors utilized the Natural transform
Samia Bushnaq, Amjad Ali, Abdullah
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source