Results 51 to 60 of about 663,265 (283)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A novel computing three-dimensional differential transform method for solving fuzzy partial differential equations

Ain Shams Engineering Journal, 2016
In this paper, we introduce three-dimensional fuzzy differential transform method and we utilize it to solve fuzzy partial differential equations. This technique is a successful method because of reducing such problems to solve a system of algebraic ...
Farshid Mirzaee, Mohammad Komak Yari
doaj   +1 more source

Combination of inverse spectral transform method and method of characteristics: deformed Pohlmeyer equation

, 2008
We apply a version of the dressing method to a system of four dimensional nonlinear Partial Differential Equations (PDEs), which contains both Pohlmeyer equation (i.e.
Bogdanov L V, Pohlmeyer K, Pohlmeyer K, Santini P M, Tsarev S P, Whitham J B, Zakharov V E, Zakharov V E, Zakharov V E, Zakharov V E, Zenchuk A I, Zenchuk A I, Zerrcxux A I, Zerrcxux A I   +13 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Exact differential transform method and semi-analytic Chebyshev collocation method for ordinary differential equations

Boundary Value Problems
This article introduces two algorithms designed for solving differential equations: the differential transform method and the second-kind Chebyshev collocation method. It provides a detailed explanation of the structure and key properties of each method.
A. S. Mohamed
doaj   +1 more source

Reduced differential transform method for partial differential equations within local fractional derivative operators

Advances in Mechanical Engineering, 2016
The non-differentiable solution of the linear and non-linear partial differential equations on Cantor sets is implemented in this article. The reduced differential transform method is considered in the local fractional operator sense.
Hossein Jafari, Hassan K Jassim, Seithuti P Moshokoa, Vernon M Ariyan, Fairouz Tchier   +4 more
doaj   +1 more source

Conformable Double Laplace–Sumudu Transform Decomposition Method for Fractional Partial Differential Equations

Complexity, 2022
In this work, we proposed a new method called conformable fractional double Laplace–Sumudu transform decomposition method (CFDLSTDM) to solve fractional partial differential equations (FPDEs).This method is a combination of the Laplace–Sumudu transform ...
Jia Honggang, Zhao Yanmin
doaj   +1 more source

Approximation of the Time-Fractional Klein-Gordon Equation using the Integral and Projected Differential Transform Methods

International Journal of Mathematical, Engineering and Management Sciences, 2023
In the present investigation, a new integral transform method (NITM) and the projected differential transform method (PDTM) are used to give an analytical solution to the time-fractional Klein-Gordon (TFKG) equation.
Manoj Singh
doaj   +1 more source

Conformal symmetry breaking operators for differential forms on spheres

, 2016
We give a complete classification of conformally covariant differential operators between the spaces of $i$-forms on the sphere $S^n$ and $j$-forms on the totally geodesic hypersphere $S^{n-1}$. Moreover, we find explicit formul{\ae} for these new matrix-
Kobayashi, Toshiyuki, Kubo, Toshihisa, Pevzner, Michael   +2 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source