Results 81 to 90 of about 1,566,333 (243)

Heterogeneous Differential Privacy

open access: yesThe Journal of Privacy and Confidentiality, 2017
The massive collection of personal data by personalization systems has rendered the preservation of privacy of individuals more and more difficult. Most of the proposed approaches to preserve privacy in personalization systems usually address this issue ...
Mohammad Alaggan   +2 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

SAFETY ASSESSMENT OF THE TANK WITH DIFFERENTIAL SETTLEMENT

open access: yesJixie qiangdu, 2015
Generally the settlement of spherical tank’s foundation is difficult to ensure complete uniformity. Especially the foundation has been used for years. There is always a certain differential settlement.
LI ZhiHai, GAO HongLi, DENG FeiZhong
doaj  

Formulation and characterization of transdermal drug delivery system comprising esomeprazole

open access: yesBLDE University Journal of Health Sciences
INTRODUCTION: Esomeprazole is an antacid belonging to the category of proton-pump inhibitors. OBJECTIVE: The key objective of the present effort was to formulate and analyze the transdermal patch of esomeprazole using polymers, permeability enhancers, as
Sudha Patil   +9 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Cubic power functions with optimal second-order differential uniformity [PDF]

open access: yes
We discuss the second-order differential uniformity of vectorial Boolean functions. The closely related notion of second-order zero differential uniformity has recently been studied in connection to resistance to the boomerang attack.
Sălăgean, Ana, O\u27Reilly, Connor
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Influence of heating elements layout on temperature uniformity in a large size heat treatment furnace

open access: yesCase Studies in Thermal Engineering
Computational Fluid Dynamics simulations were used to optimize heating elements placement on the walls of a large size electrical heat treatment furnace in order to reduce temperature gradients within the furnace and uneven temperatures on different ...
Sajad Mirzaei   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

An algorithm for generating cryptographically stable S-box optimized for programmable logic integrated circuits

open access: yesНаучно-технический вестник информационных технологий, механики и оптики
Cryptographic primitives implemented on Field-Programmable Gate Array (FPGA) have a number of advantages over their software counterparts; they are more efficient in terms of performance and energy consumption.
I. V. Shibakin   +2 more
doaj   +1 more source

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