Results 41 to 50 of about 3,377 (218)
Edulab: Majalah Ilmiah Laboratorium PendidikanPurpose – This study explores teachers' perceptions of the Implementation of the Merdeka Curriculum at SMA Muhammadiyah 5 Yogyakarta. It aims to identify challenges and conveniences faced by teachers during its application, focusing on how the curriculum'
Ica Lalitya Kusuma +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Differential Replication in Machine Learning
CoRR, 2020 8 pages, 1 Figure, 34 ...
Irene Unceta, Jordi Nin, Oriol Pujol
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Acta Paedagogica VilnensiaIndustry 4.0 era is characterized by the development of technology and the existence of flexible and effective data exchange. This has an impact on the emergence of new jobs that require the ability to solve problems effectively and efficiently ...
Dewi Oktaviani, Susilo Satanti
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Shapeglot: Learning Language for Shape Differentiation [PDF]
2019 IEEE/CVF International Conference on Computer Vision (ICCV), 2019 In this work we explore how fine-grained differences between the shapes of common objects are expressed in language, grounded on images and 3D models of the objects. We first build a large scale, carefully controlled dataset of human utterances that each refers to a 2D rendering of a 3D CAD model so as to distinguish it from a set of shape-wise similar
Panos Achlioptas +4 more
openaire +3 more sources
Frontiers in EducationThis study aimed to develop and evaluate a differentiated mathematics learning model based on students' learning style characteristics, namely visual, auditory, and kinesthetic, referred to as the DiMaLS Model. Employing a Research and Development (R&
Radiatul Adawiah +3 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Differentially Private Online Learning
CoRR, 2011 In this paper, we consider the problem of preserving privacy in the online learning setting. We study the problem in the online convex programming (OCP) framework---a popular online learning setting with several interesting theoretical and practical implications---while using differential privacy as the formal privacy measure.
Prateek Jain 0002 +2 more
openaire +3 more sources