Results 191 to 200 of about 101,301 (304)

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Chronotherapeutic optimization of radioactive iodine therapy in differentiated thyroid cancer: The rationale for evening administration. [PDF]

World J Exp Med
Meristoudis G, Savvidis C, Ilias I.
europepmc   +1 more source

Cost‐Effectiveness and Efficiency of Day Surgery Versus Elective Operations in Patients With Thyroid Neoplasms: A Multicenter Retrospective Cohort Study in China

iNew Medicine, EarlyView.
ABSTRACT Day surgery for thyroid malignancies is gaining traction globally, yet comprehensive health economic evaluations in China remain limited. This study evaluates the cost‐effectiveness and safety of thyroid day surgery versus elective inpatient operations using a large‐scale multicenter dataset.
Ying Wang, Hui Sun
wiley   +1 more source

Conditional survival and prognostic nomogram for distant metastatic differentiated thyroid cancer after total thyroidectomy. [PDF]

Sci Rep
Guo H, Qi Y, Zhang J, Wu J, Sun C.
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Brain Metastases From Differentiated Thyroid Cancer in the Era of Targeted Therapies: A Multi-Center Retrospective Cohort. [PDF]

Head Neck
Kampel L, Edalati S, Yosefof E, Warshavsky A, Horowitz G, Muhanna N, Shoffel-Havakuk H, Robenshtok E, Popovtzer A, Finkel I.   +9 more
europepmc   +1 more source

Management of differentiated thyroid cancer [PDF]

Indian Journal of Surgery, 2009
openaire   +2 more sources

Deep learning‐based prediction of cervical lymph node metastasis and genetic alterations from whole‐slide images of thyroid cancer frozen sections

Interdisciplinary Medicine, EarlyView.
Deep learning models accurately predict cervical lymph node metastasis and key genetic mutations (BRAF/TERT) directly from thyroid cancer frozen sections. This AI‐driven pipeline provides a rapid real‐time tool to guide intraoperative surgical decisions, helping to optimize surgical extent and prevent both over‐ and under‐treatment without the need for
Mingxing Qiu, Jinbang Li, Shujing Guo, Danyi Li, Chengyu Lu, Chenglong Zhao, Jiankun He, Hanxi Wang, Qiao Bai, Aihetaimu Aimaier, Zhijian Cen, Rui Mao, Zimo Ye, Jiaxue Zang, Zhining Zhuo, Lijuan Qu, Yueping Liu, Jing Cui, Xiaohong Yao, Xiuwu Bian, Li Liang   +20 more
wiley   +1 more source

Development and validation of a machine learning model for predicting high-risk distant metastatic recurrence in differentiated thyroid cancer. [PDF]

Front Med (Lausanne)
Yang F, Zhang J, Liu T, Zhao Z.
europepmc   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source