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Mitogen-Activated Protein Kinase Pathway Inhibition for Redifferentiation of Radioiodine Refractory Differentiated Thyroid Cancer: An Evolving Protocol

Thyroid, 2019
Background: Some patients with metastatic differentiated thyroid cancer (DTC) lack iodine avidity and are therefore unsuitable for radioactive iodine (RAI) therapy. Limited experience suggests that single-agent selective mitogen-activated protein kinase (
A. Iravani   +8 more
semanticscholar   +1 more source

Recurrent Differentiated Thyroid Cancer

Endocrine Practice, 2012
To discuss the risk of recurrence in patients with differentiated thyroid cancer and emphasize the importance of risk-group stratification.Common risk factors associated with recurrent thyroid cancer are outlined, and appropriate management strategies are reviewed.The overall prognosis in patients with differentiated thyroid cancer is excellent ...
openaire   +2 more sources

Radioactive Iodine Therapy in Differentiated Thyroid Cancer: 2020 Update.

AJR. American journal of roentgenology, 2020
OBJECTIVE. The paradigm of theranostics is based on tailoring therapy for the purpose of optimizing outcomes. This principle is being applied to radioactive iodine therapy. Consequently, thyroid cancer therapy protocols are evolving.
A. Ciarallo, J. Rivera
semanticscholar   +1 more source

Well differentiated thyroid cancer

Current Opinion in Oncology, 2003
Cancers of follicular cell origin are the most common of the endocrine malignancies. Thyroid cancers are seen with increased frequency after radiation exposure and in some familial syndromes. Interestingly, the prognosis of thyroid carcinoma is highly dependent on the age of the patient at the time of examination: several clinical staging systems ...
openaire   +2 more sources

Differentiated thyroid cancer – 2009

Orvosi Hetilap, 2011
Three years ago continental guidelines were published referring management and follow-up of low risk thyroid cancer patients. The aim of this paper is to summarize the changes and new directions in this field. High risk patients require another protocol. Neck ultrasound plays important role in differential diagnosis and in detecting recurrences.
openaire   +2 more sources

Survival in Differentiated Thyroid Cancer: Comparing the AJCC Cancer Staging Seventh and Eighth Editions

Thyroid, 2018
Background: The American Joint Committee on Cancer Cancer Staging System for differentiated thyroid cancer has been recently revised. The purpose of this study was to compare survival prognostication between the seventh and eighth editions. Materials and
S. Tam   +15 more
semanticscholar   +1 more source

Thyroid Isthmusectomy for Well-Differentiated Thyroid Cancer

Annals of Surgical Oncology, 2010
The American Thyroid Association guidelines do not mention isthmusectomy as an appropriate procedure for thyroid cancer. Despite this, a small number of patients present with lesions isolated to the thyroid isthmus, which can be excised without exploring the trachyesophageal grooves or total thyroidectomy. This study was designed to analyze outcomes in
Iain J, Nixon   +6 more
openaire   +2 more sources

Radioiodine Refractory Differentiated Thyroid Cancer

2022
Patients with radioactive iodine (RAI) refractory locally advanced or metastatic differentiated thyroid cancer have a poor prognosis. This article reviews the definition of RAI-refractory thyroid cancer and the management approach. Watchful waiting should be considered for patients with asymptomatic and non-progressive disease, while oral targeted ...
Wendy W L, Chan   +2 more
openaire   +2 more sources

Differentiated thyroid cancer in children

Head & Neck Surgery, 1985
AbstractDifferentiated thyroid cancer in children remains a controversial disease entity. Its incidence has markedly declined over the last decade since the use of radiotherapy in the treatment of benign conditions of the head, neck, and thorax was abandoned. Other etiologic factors have become relatively more important.
L F, De Keyser, A J, Van Herle
openaire   +2 more sources

Exploratory analysis of prognostic factors for lenvatinib in radioiodine‐refractory differentiated thyroid cancer

Head and Neck, 2019
Multitarget kinase inhibitors (m‐TKI), including lenvatinib, are now available as treatment options for radioiodine‐refractory differentiated thyroid cancer (RR‐DTC).
C. Suzuki   +12 more
semanticscholar   +1 more source

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