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Radioiodine refractory differentiated thyroid cancer

Critical Reviews in Oncology/Hematology, 2018
Differentiated thyroid cancer (DTC) is usually curable with surgery, radioactive iodine (RAI), and thyroid-stimulating hormone (TSH) suppression. However, local recurrence and/or distant metastases occur in approximately 15% of cases during follow-up, and nearly two-thirds of these patients will become RAI-refractory (RR-DTC) with a poor prognosis ...
Yuchen, Jin   +4 more
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Thyroid Nodules and Differentiated Thyroid Cancer

2014
The incidence of thyroid nodules and thyroid cancer has increased over the last several decades. This change is influenced by several factors, to include the status of iodine sufficiency, access to the health care system and, perhaps most significantly, the increased use of radiological imaging.
openaire   +2 more sources

Thyroglobulin in differentiated thyroid cancer

Clinica Chimica Acta, 2015
Identification of differentiated thyroid cancer (DTC) is becoming increasingly common. Patients usually have an excellent prognosis. Most undergo total thyroidectomy, radioiodine ablation and treatment with suppressive doses of levothyroxine. Patients require long term follow-up which includes measurement of serum thyroglobulin (Tg).
Carol, Evans   +2 more
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Effect of Tumor Size and Minimal Extrathyroidal Extension in Patients with Differentiated Thyroid Cancer

Thyroid, 2018
Introduction: Risk-stratified treatment strategies have become a focus in the treatment of differentiated thyroid cancer (DTC). In the 2015 American Thyroid Association treatment guidelines, adjuvant treatment with radioactive iodine (RAI) is considered ...
S. Tam   +11 more
semanticscholar   +1 more source

[Differentiated thyroid cancer].

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 1991
In the interval 1979-1988, out of 1070 operated goiters 77 malignant thyroid tumors were recorded, 60 of them being differentiated: papillary--32 (53.4%), vesicular--12 (20%), mixed forms--16 (26.7%). The differentiated thyroid carcinomas had peculiar clinical biological and prognostic features and were framed: stage I--60%, stage II--23.4% and state ...
M, Chifan   +9 more
openaire   +1 more source

Locally advanced differentiated thyroid cancer

Surgical Oncology, 2003
Although most patients with differentiated thyroid cancer (DTC) of follicular cell origin enjoy a relatively good prognosis, some patients unfortunately present with or develop locally advanced DTC which leads to significant local morbidity and mortality. DTC accounts for 54-94% of all locally advanced thyroid cancers.
Electron, Kebebew, Orlo H, Clark
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Radioiodine Refractory Differentiated Thyroid Cancer: Time to Update the Classifications

Thyroid, 2018
Background: The management of aggressive and progressing metastatic differentiated thyroid cancer (DTC) is very difficult, and the determination as to when such patients are refractory to 131I therapy (e.g., radioiodine refractory) is problematic and ...
D. Van Nostrand
semanticscholar   +1 more source

Differentiated thyroid cancer: an update

Current Opinion in Oncology, 2011
The incidence of differentiated thyroid cancer (DTC) is increasing. There remains controversy regarding several aspects of its management, including the need for prophylactic central compartment neck dissection and use of recombinant human thyroid stimulating hormone (rhTSH) for ¹³¹I radioactive iodine remnant ablation in patients with low-risk disease.
Tracy S, Wang   +2 more
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Thyroid hormone-producing metastases in differentiated thyroid cancer

Journal of Endocrinological Investigation, 1996
Thyroid hormone production by metastases of differentiated thyroid carcinoma is very rare and its pathogenesis is still unknown. The aim of this study was to present some clinical and demographic evidence that thyroid hormone-producing metastases of differentiated thyroid carcinoma are related to environmental factors, probably iodine deficiency.
J L, Gross, I, Vasques Moraes
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Anaplastic Thyroid Carcinoma: Association With Differentiated Thyroid Cancer

Archives of Otolaryngology - Head and Neck Surgery, 1988
Fourteen cases of anaplastic thyroid carcinoma (ATC) treated at Baylor College of Medicine, Houston, during a 19-year period were reviewed. There was a 1.3:1 female preponderance, and the median patient age was 62 years. Ten (71%) of the anaplastic tumors either followed or occurred simultaneously with a well-differentiated thyroid carcinoma.
J R, Spires, M R, Schwartz, R H, Miller
openaire   +2 more sources

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