Results 221 to 230 of about 1,127,844 (304)

Network based approach identifies miR‐145‐3p as a central regulatory hub associated to the progression from localized to metastatic medullary thyroid carcinoma

open access: yesThe Journal of Pathology, EarlyView.
Abstract Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor originating from calcitonin producing C‐cells and accounts for 1–5% of thyroid cancers. Total thyroidectomy is curative in localized disease (N0), whereas lymph node metastases (N1) are associated with poorer prognosis.
Anna Citarella   +24 more
wiley   +1 more source

Molecular Diagnostics and Personalized Therapeutics in Differentiated Thyroid Carcinoma: A Clinically Oriented Review. [PDF]

open access: yesDiagnostics (Basel)
Coca-Pelaz A   +7 more
europepmc   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

open access: yesPrecision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang   +7 more
wiley   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta   +9 more
wiley   +1 more source

Immunotherapy response in microsatellite-stable poorly differentiated thyroid carcinoma with mismatch repair deficiency and high tumor mutational burden. [PDF]

open access: yesArch Endocrinol Metab
Feldmann JH   +6 more
europepmc   +1 more source

Gold‐Modified Mesoporous Carbon Enables Serum Metabolic Fingerprinting for Papillary Thyroid Carcinoma Diagnosis

open access: yesSmall Methods, EarlyView.
A novel MCHS‑Au‑LA substrate is developed for carbon‑gold nanostructure‐initiator mass spectrometry (C‑Au‑NIMS), which acquires metabolic fingerprints of serum samples from papillary thyroid carcinoma (PTC), benign thyroid nodules (BTN), and healthy controls (HC).
Wanwan Yi   +8 more
wiley   +1 more source

Risk factors and outcomes of metastatic poorly differentiated thyroid carcinoma. [PDF]

open access: yesWorld J Clin Cases
Hsu CW   +5 more
europepmc   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho   +7 more
wiley   +1 more source

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