Results 21 to 30 of about 21,306 (227)

DEVELOPMENT OF MEASUREMENT METHODOLOGIES IN METROLOGY FOR CELL BIOLOGY AND REGENERATIVE MEDICINE [PDF]

, 2013
Aim of this thesis is the development of measurement methodologies in metrology for cell biology and regenerative medicine. Regenerative medicine is a novel branch of medicine based on the use of autologous stem cells and biocompatible medical devices to
Cardile, Diego, Crisafulli, Daniela, Divieto, Carla   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The institution of yasyr among the Nogais: the transformation of nomadic society in the imperial period

Nomadic Civilization: Historical Research
The article provides a comprehensive analysis of the transformation of the yasyr institution (captives taken during military conflicts is a part of the raid-based economy) among the Nogai people during the 17th–19th centuries, within the context of their
A. T. Dzhumagulova
doaj   +1 more source

Research on the Governance Dilemmas and Resilience Improvement in Old and Dilapidated Communities from the Perspective of Risk Inequality

Fengjing Yuanlin
ObjectiveAmid rapid urbanization and the increasing frequency of extreme climate events, urban systems are facing escalating systemic risks. As the fundamental unit of urban governance, community resilience — the capacity to withstand, adapt to, and ...
Yuefang RONG, Jian SONG, Haoxi LIN, Mengyuan JIA   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

A course on integration theory: including more than 150 exercises with detailed answers [PDF]

, 2014
This textbook provides a detailed treatment of abstract integration theory, construction of the Lebesgue measure via the Riesz-Markov Theorem and also via the Carathéodory Theorem. It also includes some elementary properties of Hausdorff measures as well
Lerner, Nicolas
core   +1 more source

Differentiable and Self-Auditing Transient Dynamics Solver for Ball Bearings: OpenBEARD Cross-Verified Against ADORE

Applied Sciences
A transient multibody dynamics simulation of rolling-element bearings is the basis for the design of high-speed rotating machinery; however, the established solvers are proprietary, cannot be used with automatic differentiation, and offer no built-in ...
Xinlu Yu, Kai Wang, Yuchen Han, Yingqian Fu   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source