Results 21 to 30 of about 64,922 (190)
Severe, Non‐apneic Respiratory Dysfunction and Hypoxia following Generalized Convulsive Seizures
Objective Sudden unexpected death in epilepsy (SUDEP) is a devastating consequence of some generalized convulsive seizures (GCS). Recent work has focused on seizure related apnea as a biomarker of SUDEP risk, frequently without characterizing the adequacy of non‐apneic ventilation or identifying other dysfunctional breathing patterns.
Haley E. Pysick +9 more
wiley +1 more source
Abstract Simulation‐based training is critical for surgical skill acquisition and typically uses soft‐preserved body donors, as they represent high‐fidelity models (vs. hard‐fixed donors) with prolonged periods of preservation (vs. unembalmed donors).
Sorin Darie +13 more
wiley +1 more source
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart +7 more
wiley +1 more source
ABSTRACT Backgrounds Accurate stent positioning in aorto‐ostial lesions remains challenging due to complex three‐dimensional anatomy, lack of optimal fluoroscopic projections, and high rates of geographic miss. Stent overhang impairs guide catheter re‐engagement and complicates future revascularization.
Gregor Leibundgut +7 more
wiley +1 more source
Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf +9 more
wiley +1 more source
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray +2 more
wiley +1 more source
Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan +14 more
wiley +1 more source
We designed and synthesized a dual‐type AIE photosensitizer (named TB) spray, containing a cationic quaternary ammonium unit and a glycosyl‐targeted boronic acid moiety, characterized for the elimination of biofilm infections of Candidozyma auris (C. auris) on high‐touch surfaces.
Xiaoyu Xu +16 more
wiley +1 more source
Abstract Objective The aim of the present study was to analyze breastfeeding rates and duration in relation to preterm birth, fetal growth restriction, and demographics over five decades. Methods This retrospective cohort study included 1559 individuals (aged 4–52 years) and their parents from the University Medical Center Mainz, Germany.
Achim Fieß +10 more
wiley +1 more source

