Results 51 to 60 of about 4,047,917 (285)
Determinism and Causation Examples [PDF]
, 2004 In studying causation, many examples are presented assuming that determinism holds in the world of the example such as the notoriously difficult to resolve preemptive and preventative situations.
Burock, Marc
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Gatekeepers changing consumers' behaviour in energy consumption [PDF]
, 2009 Changing people's behaviour and reducing energy consumption has proved to be more difficult than attitudes or technical possibilities would imply. In this paper we discuss how to intervene the individual decisions that significantly determine energy ...
Kaskinen, Tuuli +3 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Экспериментальная психология, 2020 The study presented in this article is devoted to the problem of the influence of adults’ perceptions and interpretations of difficult life situations on their coping behavior, which is relevant in conditions of social instability and forced ...
V.D. Alperovich
doaj +1 more source
Wagering on Pragmatic Encroachment [PDF]
, 2017 Lately, there has been an explosion of literature exploring the the relationship between one’s practical situation and one’s knowledge. Some involved in this discussion have suggested that facts about a person’s practical situation might affect whether ...
Eaton, Daniel, Pickavance, Timothy
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Perception of Life Changes: The Situation Structure and Stages of Accepting Change
Национальный психологический журналBackground. Contemporary researchers explore the perception of a situation by analysing the cues of an environment and the subjective meaning attributed to the cues by an individual.
Ekaterina V. Bityutskaya
doaj +1 more source
Sustainability indicators [PDF]
, 2003 Imagine a situation where, after debating for years on what makes you happy, you finally decide that it is about time you start put these ideas into practice and effectively make yourself happy(ier). If you are really determined, you will be keen to stop
Simon, Sandrine
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