Results 21 to 30 of about 166,034,633 (120)

Molecular Imaging of Microglial Activation in Amyotrophic Lateral Sclerosis [PDF]

open access: yes, 2012
There is growing evidence of activated microglia and inflammatory processes in the cerebral cortex in amyotrophic lateral sclerosis (ALS). Activated microglia is characterized by increased expression of the 18 kDa translocator protein (TSPO) in the brain
Philippe Corcia   +29 more
core   +2 more sources

Treatment of multiple sclerosis in special populations: The case of refugees [PDF]

open access: yes, 2020
Multiple sclerosis was long considered a relatively rare entity in the Middle East, but research over the past 10 years and the publication of the Middle East North Africa Committee for Treatment and Research in Multiple Sclerosis guidelines for multiple
Yamout, Bassem I., Zeineddine, Maya M.
core   +1 more source

Time and time-frequency analysis of near-infrared signals for the assessment of ozone autohemotherapy long-term effects in multiple sclerosis [PDF]

open access: yes, 2013
Ozone autohemotherapy is an emerging therapeutic technique that is gaining increasing importance in treating neurological disorders. A validated and standard methodology to assess the effect of such therapy on brain metabolism and circulation is however ...
Molinari, Filippo   +11 more
core   +1 more source

SUMMIT (Serially Unified Multicenter Multiple Sclerosis Investigation): creating a repository of deeply phenotyped contemporary multiple sclerosis cohorts. [PDF]

open access: yes, 2018
BackgroundThere is a pressing need for robust longitudinal cohort studies in the modern treatment era of multiple sclerosis.ObjectiveBuild a multiple sclerosis (MS) cohort repository to capture the variability of disability accumulation, as well as ...
Uitdehaag, Bernard M.J.   +18 more
core   +1 more source

Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown [PDF]

open access: yes, 2010
Background: An inducible release of soluble junctional adhesion molecule-A (sJAM-A) under pro-inflammatory conditions was described in cultured non-CNS endothelial cells (EC) and increased sJAM-A serum levels were found to indicate inflammation in non ...
Romero, Ignacio   +32 more
core   +1 more source

Imaging Microglial/Macrophage Activation in Spinal Cords of Experimental Autoimmune Encephalomyelitis Rats by Positron Emission Tomography Using the Mitochondrial 18kDa Translocator Protein Radioligand [18F]DPA-714 [PDF]

open access: yes, 2012
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. Activated microglia/macrophages play a key role in the immunopathogenesis of MS and its corresponding animal models, experimental autoimmune encephalomyelitis (EAE).
Thézé, Benoit   +8 more
core   +1 more source

The development of a scale of the Guttman Type for the assessment of mobility disability in multiple sclerosis [PDF]

open access: yes, 1999
Objective: The aim of the study was to develop a valid and reliable unidimensional scale of the Guttman type for the assessment of mobility disability in multiple sclerosis (MS).
De Souza, LH
core   +1 more source

A grounded theory analysis of the occupational impact of caring for a partner who has multiple sclerosis [PDF]

open access: yes, 2006
Chronic progressive conditions such as multiple sclerosis impact engagement in and orchestration of daily occupations by people with the condition, and their family members.
Molineaux, M   +7 more
core   +1 more source

Coexistence of diabetes mellitus type 1 with diffuse systemic sclerosis – case report and literature review [PDF]

open access: yes, 2017
Diabetic sclerodactyly is a frequently recognized skin finding that may occur in patients with diabetes mellitus but coexistence of diabetes and systemic sclerosis is rare.
Maria Kurowska   +3 more
core   +1 more source

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