Results 121 to 130 of about 1,308,954 (287)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Satellite Retrieval of Downwelling Shortwave Surface Flux and Diffuse Fraction under All Sky Conditions in the Framework of the LSA SAF Program (Part 2: Evaluation)

open access: yesRemote Sensing, 2019
High frequency knowledge of the spatio-temporal distribution of the downwelling surface shortwave flux (DSSF) and its diffuse fraction (fd) at the surface is nowadays essential for understanding climate processes at the surface−atmosphere interface,
Dominique Carrer   +5 more
doaj   +1 more source

Linear Boltzmann equation and fractional diffusion

open access: yesKinetic & Related Models, 2018
25 pages, no ...
Bardos, Claude   +2 more
openaire   +6 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

DISTRIBUTED ORDER FRACTIONAL SUB-DIFFUSION [PDF]

open access: yesFractals, 2004
A distributed order fractional diffusion equation is considered. Distributed order derivatives are fractional derivatives that have been integrated over the order of the derivative within a given range. In this paper, sub-diffusive cases are considered. That is, the order of the time derivative ranges from zero to one.
openaire   +3 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

CO-dark Molecular Gas Traced by HCO+ in the Diffuse Interstellar Medium

open access: yesThe Astrophysical Journal
A classic problem in the study of the interstellar medium (ISM) is the near-invisibility of molecular hydrogen (H _2 ) in cold environments. Observations of CO emission are typically used to indirectly trace H _2 , but a significant fraction of H _2 in ...
Daniel R. Rybarczyk   +4 more
doaj   +1 more source

Effect of diffusion of light on thin-film photovoltaic laminates

open access: yesResults in Physics, 2016
A large fraction of the daylight incident on building-integrated photovoltaic (BIPV) laminates is diffuse irradiance. In this study, fabrics of various weaves were used to simulate combinations of direct and diffuse irradiance on façade-mounted PV.
Lipi Mohanty, Stephen K. Wittkopf
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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