Results 41 to 50 of about 202,276 (321)

The small FOXP1 isoform predominantly expressed in activated B cell-like diffuse large B-cell lymphoma and full-length FOXP1 exert similar oncogenic and transcriptional activity in human B cells

Haematologica, 2017
The forkhead transcription factor FOXP1 is generally regarded as an oncogene in activated B cell-like diffuse large B-cell lymphoma. Previous studies have suggested that a small isoform of FOXP1 rather than full-length FOXP1, may possess this oncogenic ...
Martine van Keimpema, Leonie J. Grüneberg, Esther J.M. Schilder-Tol, Monique E.C.M. Oud, Esther A. Beuling, Paul J. Hensbergen, Johann de Jong, Steven T. Pals, Marcel Spaargaren   +8 more
doaj   +1 more source

Diffuse large B-cell lymphoma with uncommon cardiac invasion

SAGE Open Medical Case Reports, 2022
Diffuse large B-cell lymphoma is the most common histologic subtype of non-Hodgkin lymphoma. Secondary involvement of the heart is seen late in advanced cases, it is uncommon for diffuse large B-cell lymphoma to present as intracardiac mass.
Yunis Daralammouri, Hamza Hamayel, Yahya Ismail, Sajed Majadla, Razan Odeh   +4 more
doaj   +1 more source

Глобализация как фактор радикализации трансформации приоритетов социально-экономического развития в посттранзитивних экономиках [PDF]

, 2011
Expression of the for khead transcription factor FOXP1 is essential for early B-cell development, whereas down regulation ofFOXP1at the germinal center (GC) stage is required for GC B-cell function. Aberrantly high FOXP1 expression is frequently observed
Banham, Basso, Bende, Bende, Berkowska, Berkowska, Ding, Dogan, Engels, Fenton, Fornek, Goldstein, Gutiérrez, Hans, Horikawa, Hu, Iida, Iqbal, Klein, Kocemba, Kometani, Kuo, Kwon, Lenz, Lenz, Leonie J. Grüneberg, Lin, Liu, Mandelbaum, Marcel Spaargaren, Martin, Martine van Keimpema, McHeyzer-Williams, Menno C. van Zelm, Michal Mokry, Nera, Nutt, Ochiai, Pape, Paul Coffer, Rampanelli, Ruben van Boxtel, Rui, Sagaert, Sagardoy, Scheeren, Schmidlin, Sciammas, Seifert, Shaffer, Shaffer, Shaffer, Shaffer, Shapiro-Shelef, Staudt, Steven T. Pals, Streubel, Taylor, Tunyaplin, van Boxtel, van Keimpema, Vegliante, Yoshida, Zuccarino-Catania   +63 more
core   +2 more sources

Post-CAR-T cell therapy presenting as proteinaceous lymphadenopathy

Human Pathology: Case Reports, 2021
Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma and is often treated with chemotherapy, autologous stem cell transplant, and chimeric antigen receptor (CAR-T) cell therapy.
Mishi Bhushan, Kirthi R. Kumar
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Overexpression of FoxM1 offers a promising therapeutic target in diffuse large B-cell lymphoma

Haematologica, 2012
Background FoxM1 has been shown to play a critical role in the pathogenesis of various epithelial malignancies. However, its role in lymphoid malignancies has not been fully clarified.
Shahab Uddin, Azhar R Hussain, Maqbool Ahmed, Khawar Siddiqui, Fouad Al-Dayel, Prashant Bavi, Khawla S. Al-Kuraya   +6 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

Case of Gastric Diffuse Large B-Cell Lymphoma

Case Reports in Oncology, 2019
The gastrointestinal (GI) tract is the predominant site of extra nodal lymphoma involvement. In the United States (US), gastric lymphoma is the most common extra nodal site of lymphoma.
Usman A. Pirzada, Kishore Kumar, Hassan Tariq, Masooma Niazi, Jasbir Makker   +4 more
doaj   +1 more source

Non-Hodgkin’s Lymphoma in Buccal Vestibule -Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2014
Lymphomas are malignant neoplasms arising from lymphocytes B cell or T cell that affects mainly lymph nodes, spleen and other non hematopoietic tissues. They are classified as Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL). Diffuse large B-cell
Indira Reddy, Sreenath G, Raghavendra Readdy Y, Ravi Prakash .A, Swathi T R   +4 more
doaj   +1 more source