Results 61 to 70 of about 264,257 (370)

Post-CAR-T cell therapy presenting as proteinaceous lymphadenopathy

Human Pathology: Case Reports, 2021
Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma and is often treated with chemotherapy, autologous stem cell transplant, and chimeric antigen receptor (CAR-T) cell therapy.
Mishi Bhushan, Kirthi R. Kumar
doaj   +1 more source

Глобализация как фактор радикализации трансформации приоритетов социально-экономического развития в посттранзитивних экономиках [PDF]

, 2011
Expression of the for khead transcription factor FOXP1 is essential for early B-cell development, whereas down regulation ofFOXP1at the germinal center (GC) stage is required for GC B-cell function. Aberrantly high FOXP1 expression is frequently observed
Banham, Basso, Bende, Bende, Berkowska, Berkowska, Ding, Dogan, Engels, Fenton, Fornek, Goldstein, Gutiérrez, Hans, Horikawa, Hu, Iida, Iqbal, Klein, Kocemba, Kometani, Kuo, Kwon, Lenz, Lenz, Leonie J. Grüneberg, Lin, Liu, Mandelbaum, Marcel Spaargaren, Martin, Martine van Keimpema, McHeyzer-Williams, Menno C. van Zelm, Michal Mokry, Nera, Nutt, Ochiai, Pape, Paul Coffer, Rampanelli, Ruben van Boxtel, Rui, Sagaert, Sagardoy, Scheeren, Schmidlin, Sciammas, Seifert, Shaffer, Shaffer, Shaffer, Shaffer, Shapiro-Shelef, Staudt, Steven T. Pals, Streubel, Taylor, Tunyaplin, van Boxtel, van Keimpema, Vegliante, Yoshida, Zuccarino-Catania   +63 more
core   +2 more sources

Derepressing of STAT3 and USP7 contributes to resistance of DLBCL to EZH2 inhibition

Heliyon, 2023
Diffuse large B-cell lymphoma is the most common subtype of lymphoma, representing ∼25 % of non-Hodgkin lymphoid malignancies. EZH2 is highly expressed in Diffuse large B-cell lymphoma and ∼22 % of patients contain EZH2 mutations.
Chenyun He, Wenbin Zhou, Xiaoxia Jin, Haining Zhou   +3 more
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Overexpression of FoxM1 offers a promising therapeutic target in diffuse large B-cell lymphoma

Haematologica, 2012
Background FoxM1 has been shown to play a critical role in the pathogenesis of various epithelial malignancies. However, its role in lymphoid malignancies has not been fully clarified.
Shahab Uddin, Azhar R Hussain, Maqbool Ahmed, Khawar Siddiqui, Fouad Al-Dayel, Prashant Bavi, Khawla S. Al-Kuraya   +6 more
doaj   +1 more source

Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile [PDF]

, 2009
The human REL proto-oncogene encodes a transcription factor in the nuclear factor (NF)-kappaB family. Overexpression of REL is acutely transforming in chicken lymphoid cells, but has not been shown to transform any mammalian lymphoid cell type.
Chin, M., Gilmore, T.D., Herscovitch, M., Waxman, D.J., Zhang, N.   +4 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

Case of Gastric Diffuse Large B-Cell Lymphoma

Case Reports in Oncology, 2019
The gastrointestinal (GI) tract is the predominant site of extra nodal lymphoma involvement. In the United States (US), gastric lymphoma is the most common extra nodal site of lymphoma.
Usman A. Pirzada, Kishore Kumar, Hassan Tariq, Masooma Niazi, Jasbir Makker   +4 more
doaj   +1 more source

Non-Hodgkin’s Lymphoma in Buccal Vestibule -Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2014
Lymphomas are malignant neoplasms arising from lymphocytes B cell or T cell that affects mainly lymph nodes, spleen and other non hematopoietic tissues. They are classified as Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL). Diffuse large B-cell
Indira Reddy, Sreenath G, Raghavendra Readdy Y, Ravi Prakash .A, Swathi T R   +4 more
doaj   +1 more source