Results 51 to 60 of about 19,353 (291)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Study of Diffusible Behavior of Hydrogen in First Generation Advanced High Strength Steels

open access: yesMetals, 2021
This study deals with microstructural influence on the H permeation behavior of Dual-Phase (DP) and Complex Phase (CP) steels using electrochemical permeation studies.
Dwaipayan Mallick   +3 more
doaj   +1 more source

Influence of M-phase chromatin on the anisotropy of microtubule asters [PDF]

open access: yes, 1996
In many eukaryotic cells going through M-phase, a bipolar spindle is formed by microtubules nucleated from centrosomes. These microtubules, in addition to being "captured" by kinetochores, may be stabilized by chromatin in two different ways: short-range
Dogterom, M.   +3 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Influence of CO2 and H2S Concentration on Hydrogen Permeation Behavior of P110 Steel

open access: yesInternational Journal of Electrochemical Science, 2017
The effect of CO2 and H2S concentration on the electrochemical and hydrogen permeation behaviors of P110 steel was investigated separately. The results showed that the corrosion current density was enhanced, while the polarization resistance and charge ...
Shuliang Wang   +6 more
doaj   +1 more source

Development of eye colors in Drosophila: some properties of the hormones concerned [PDF]

open access: yes, 1938
The substance inducing the production of pigment in the eyes of vermilion brown mutants of Drosophila melanogaster has been shown to be a relatively stable chemical entity possessing true hormone-like activity.
Beadle, G. W., Tatum, Edward L.
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Development of Eye Colors in Drosophila: Extraction of the Diffusible Substances Concerned [PDF]

open access: yes, 1937
The development of eye color in Drosophila is known to involve special diffusible substances [1,2]. A genetically vermilion (v) eye will develop wild-type eye color if it is supplied with v+ substance by transplantation or by injection of body fluid of ...
Beadle, G. W., Thimann, Kenneth V.
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Method for diffusible hydrogen analysis in welding materials by gas chromatography

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2004
A new method was developed by gas chromatography for diffusible hydrogen analysis in E-7018 ordinary electrodes, using a packed column and nitrogen as reference and carrier gas.
Ramón Piloto Rodríguez   +2 more
doaj   +1 more source

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