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Morphometric model for pulmonary diffusing capacity I. Membrane diffusing capacity
Respiration Physiology, 1993The pulmonary diffusing capacity is related to the quantitative design characteristics of the pulmonary gas exchanger. The current model for estimating DLO2 from morphometric data breaks the diffusion path for O2 into four steps, three of which represent the membrane part of DLO2.
R. Vock +6 more
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, 2005 Transfer of oxygen and carbon dioxide over the alveolocapillary membrane is the main function of the lungs and can be measured by the diffusing capacity for carbon monoxide (CO). CO has a high affinity for hemoglobin and is absent in pulmonary capillary blood.
J.C. de Jongste +2 more
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Carbon Monoxide Diffusing Capacity
Clinics in Chest Medicine, 1989Before measuring single-breath DLCO it is important to: (1) standardize carefully test technique and computation using current ATS guidelines; (2) confirm that computerized systems correctly perform the calculations; and (3) confirm that the reference values selected are consistent with the data produced by the device in the laboratory by comparing ...
Robert E. Forster, Robert O. Crapo
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Pulmonary diffusing capacity of athletes
Journal of Applied Physiology, 1963Champion swimmers have been found to have significantly higher steady-state pulmonary diffusing capacities than those measured in normal subjects of comparable age at the same exercise level. Nonactive and moderately active normal subjects, swimmers of average ability, long distance runners, and older ex-athletes were found to show no significant ...
L. G. Bentivoglio +4 more
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Clinical Reviews in Allergy & Immunology, 2009
The diffusing capacity for carbon monoxide (DL(CO)) is a commonly performed and clinically useful pulmonary function test that provides a quantitative measure of gas transfer in the lungs. It is valuable for evaluating and managing patients with a wide variety of pulmonary disorders, especially patients with interstitial lung disease, pulmonary ...
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The diffusing capacity for carbon monoxide (DL(CO)) is a commonly performed and clinically useful pulmonary function test that provides a quantitative measure of gas transfer in the lungs. It is valuable for evaluating and managing patients with a wide variety of pulmonary disorders, especially patients with interstitial lung disease, pulmonary ...
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The Reliability of the Pulmonary Diffusing Capacity Determination
Scandinavian Journal of Clinical and Laboratory Investigation, 1962The test-retest reliability of the ten second breath-holding method for the determination of pulmonary diffusing capacity of carbon monoxide was studied in a series of 151 men and women, including patients, normal subjects and athletes.The mean and standard deviation of the DLCO was 28.2 ± 10.09 ml × min−1 × mmHg−1.
M. J. Karvonen +2 more
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1991
The transport of the respiratory gases O2 and CO2 between ambient medium “air” and the internal medium “blood” is ensured by three basic mechanisms: ventilation, diffusion and perfusion.
H. Burchardi, T. Stokke
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The transport of the respiratory gases O2 and CO2 between ambient medium “air” and the internal medium “blood” is ensured by three basic mechanisms: ventilation, diffusion and perfusion.
H. Burchardi, T. Stokke
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Diffusion Capacity in Heart Transplant Recipients
Chest, 1992Preoperative diffusion capacity per liter alveolar volume (Kco) in cardiac transplant recipients with an intrinsic normal lung is within the normal range. In the first postoperative year, Kco showed a significant mean decrease of 12 percent (p less than 0.004). Lung function (TLC, VC, FEV1) tended to normalize after heart transplantation.
C. Hilvering +5 more
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Diffusing capacity of the lung in pulmonary emphysema
Journal of Applied Physiology, 1964Steady-state CO and O2 methods for measuring pulmonary diffusing capacity may be affected by abnormal distribution of inspired gas relative to perfusion. These methods frequently fail to separate abnormalities in diffusion from abnormalities in distribution in patients with obstructive emphysema.
Ruth G. Armstrong +2 more
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The effect of tiotropium on the pulmonary diffusing capacity
Methods and Findings in Experimental and Clinical Pharmacology, 2007To our knowledge, there is no data on the effect of tiotropium on pulmonary gas exchange in healthy subjects. The aim of this study was to assess the effects of tiotropium on pulmonary diffusing capacity. Twenty-one healthy volunteers were enrolled for a prospective, randomized, double-blind, placebo-controlled study.
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